OptimalCutpoints statistics

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OptimalCutpoints specifications

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Unique identifier OMICS_26843
Name OptimalCutpoints
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages R
Computer skills Advanced
Version 1.1-3
Stability Stable
Maintained Yes

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  • person_outline Monica Lopez <>

Publication for OptimalCutpoints

OptimalCutpoints in publications

 (29)
PMCID: 5944373
PMID: 29760869
DOI: 10.1080/20013078.2018.1470442

[…] values and bonferroni adjusted p-values., all statistical analyses were performed using r software v3.3.2 (r development core team, 2016; http://cran.r-project.org) with stats, caret, psych and optimalcutpoints package []. boxplots and volcano plots were generated with ggplot2 r package. correlations with clinical parameters such as bmi were done with cor.test function in r software, using […]

PMCID: 5896902
PMID: 29649219
DOI: 10.1371/journal.pone.0193945

[…] (roc) curves using youden methodology. statistical analyses were performed using r software (version 3.3.2, r foundation for statistical computing, vienna, austria; http://www.r-project.org) and its optimalcutpoints package for determining the optimal cut-off values., the mean age of total patients was 54.86±15.59 years. the distribution of operations and procedures included 9 cases of eswl, 2 […]

PMCID: 5784995
PMID: 29370278
DOI: 10.1371/journal.pone.0191822

[…] standard was blinded to imaging results., statistical analyses were performed by a bioinformatician (9 years of experience) using statistical software (r, version 3.2.5 including rjags, coda, proc, optimalcutpoints and mass packages, r foundation for statistical computing, vienna, austria). categorical variables were expressed as numbers and percentages. continuous variables were expressed […]

PMCID: 5731824
PMID: 29244844
DOI: 10.1371/journal.pone.0189641

[…] significant difference’ method. multivariable discriminative models were built by logistic regressions and a cut-off defined by maximizing specificity and sensitivity simultaneously (r-package optimalcutpoints). receiver operating characteristic (roc) curves, corresponding area under these roc curves (auc), and p-values are presented. (two-sided) p-values below 0.05 were considered […]

PMCID: 5708087
PMID: 29187235
DOI: 10.1186/s13104-017-2950-9

[…] ability, as conveyed by the receiver operating characteristics (roc) curve, fig. b. the sensitivity and specificity values of the mirna-derived score, at three optimal cut-off points (“optimalcutpoints” r package, using the minimization of misclassification criterion), are shown in table .table 1 ppv positive predictive value, npv negative predictive value a1.140 is the optimal […]


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OptimalCutpoints institution(s)
Universidad de Santiago de Compostela, Santiago de Compostela, Spain; Universidade de Vigo, Vigo, Spain; Complejo Hospitalario Universitario de Santiago de Compostela (CHUS), Santiago de Compostela, Spain
OptimalCutpoints funding source(s)
Supported by grants MTM2008-01603, MTM2010-09213-E and MTM2011- 28285-C02-00 from Spain’s Ministry of Science & Innovation and by Carlos III Institute of Health grant CA09/0053.

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