Assists in planning next generation sequencing (NGS) experiments. OPENDoRM can be splits into four components: (i) global settings for the NGS experiment; (ii) data processing; (iii) visual exploration; and (iv) data interpretation. It is able to: (i) describe the pooling of high-throughput generated data using four different algorithms; (ii) identify the optimal number of patients in each pool with respect to minimization of the cost of the experiment; (iii) generate easy-to-read reports and charts for better understanding the planning of the experiments.
LabGTP (Laboratory of Genomics, Transcriptomics and Proteomics), Institute for High Performance Computing and Networking (ICAR), National Research Council (CNR), Naples, Italy; Department of Computer Science, University of Naples Parthenope, Naples, Italy; Institute of Mathematics and Informatics, Vilnius University, Vilnius, Lithuania
OPENDoRM funding source(s)
Supported by INTEROMICS flagship Italian project, PON02- 00612-3461281 and PON02-00619-347045, by a grant No.MIP-051/2014 from the Research Council of Lithuania and by RSF grant 14-41-00039.