Unlock your biological data
Finding and translating stretches of DNA lacking stop codons is a task common in the analysis of sequence data. However the computational tools for finding open reading frames are sufficiently slow that they are becoming a bottleneck as the volume of sequence data grows. This computational bottleneck is especially problematic in metagenomics when searching unassembled reads, or screening assembled contigs for genes of interest.
(Woodcroft et al., 2016) OrfM: a fast open reading frame predictor for metagenomic data. Bioinformatics.