ORIOS specifications


Unique identifier OMICS_13323
Alternative name Order Restricted Inference for Oscillatory Systems
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages R
Computer skills Advanced
Version 1.0
Stability Stable
Maintained Yes




No version available


  • person_outline Shyamal Peddada

Publication for Order Restricted Inference for Oscillatory Systems

ORIOS citation


A Bootstrap Based Measure Robust to the Choice of Normalization Methods for Detecting Rhythmic Features in High Dimensional Data

Front Genet
PMCID: 5801422
PMID: 29456555
DOI: 10.3389/fgene.2018.00024

[…] algorithms available in the literature to determine whether a gene is rhythmic or not. Some recent examples include JTK_Cycle (from now on JTK) (Hughes et al., ), RAIN (Thaben and Westermark, ), and ORIOS (Larriba et al., ). The performance of such algorithms potentially depends upon, among other factors, the normalization methods used. For example, Rustici et al. (); Oliva et al. (); Peng et al. […]

ORIOS institution(s)
Departamento de Estadística e Investigación Operativa, Universidad de Valladolid, Paseo de Belén, Valladolid, Spain; Biostatistics and Computational Biology Branch, National Institute of Environmental Health Sciences (NIEHS), NC, USA
ORIOS funding source(s)
This work was supported by Spanish Ministerio de Ciencia e Innovacion [MTM2015-71217-R]; Spanish Ministerio de Educacion, Cultura y Deporte [FPU14 /04534]; Intramural Research Program of the National Institute of Environmental Health Sciences [Z01 ES101744-04].

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