OSSE statistics

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Citations per year

Number of citations per year for the bioinformatics software tool OSSE

Tool usage distribution map

This map represents all the scientific publications referring to OSSE per scientific context
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Associated diseases

This word cloud represents OSSE usage per disease context

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OSSE specifications


Unique identifier OMICS_24282
Alternative name Online Sample Size Estimator
Software type Application/Script
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline Zhuo Shaowei
  • person_outline Marie Loh
  • person_outline Adrian Mondry

OSSE citations


Association of ERAP1, IL23R and PTGER4 Polymorphisms with Radiographic Severity of Ankylosing Spondylitis

PMCID: 5366379
PMID: 28400866
DOI: 10.2174/1874312901711010001

[…] www.broadinstitute.org/mammals/haploreg/haploreg.php), for a desired power of 80% with a significance level of 5%. The minimum required sample size was calculated using the Bioinformatics Institute’s Online Sample Size Estimator (http://osse.bii.a-star.edu.sg/calculation1.php) with the assumption of the proportions of risky alleles of 65% and 40% in the severe and mild group, respectively. Severe- […]


CTTTA Deletion/Insertion polymorphism in 3' UTR of LEPR gene in type 2 diabetes subjects belonging to Kashmiri population

PMCID: 4288559
PMID: 25580385
DOI: 10.1186/s40200-014-0124-z

[…] Data were managed by Microsoft excel and Java Stat software. Power calculation of the study was performed by online statistical calculator (http://osse.bii.a-star.edu.sg/calculation2.php). The power of study measures 81.4% for observed frequency of minor alleles at 5% significance level. Statistical Package for Social Sciences (SPSS, version 20. […]


A Study on MTHFR C677T Gene Polymorphism and Alcohol Dependence among Meiteis of Manipur, India

PMCID: 4437350
PMID: 26317030
DOI: 10.1155/2014/310241
call_split See protocol

[…] al interval (CI), using the freely available 2 × 2 contingency table []. Statistical significance was considered at 5% level. Power of the study was calculated using online available software (http://osse.bii.a-star.edu.sg/index.php). […]


Lack of Association between Polymorphisms of Hepatic Lipase with Lipid Profile in Young Jordanian Adults

PMCID: 4167487
PMID: 25278769
DOI: 10.4137/LPI.S14798

[…] bers or percentages for other variables. ANOVA was used to examine the differences in polymorphisms of LIPC G-250A or C-514T for genders joined and separated. Power analysis was performed online with OSSE software (http://osse.bii.a-star.edu.sg/index.php). For a sample size of 348 cases, the power exceeded 60%. For all analysis, P < 0.05 was considered significant. […]


In Vitro Assessment of the Inflammatory Breast Cancer Cell Line SUM 149: Discovery of 2 Single Nucleotide Polymorphisms in the RNase L Gene

PMCID: 3563072
PMID: 23386909
DOI: 10.7150/jca.5002
call_split See protocol

[…] script was written in the language R based on the sample size analysis recommendations made by Pfeiffer et al., . The script was then independently verified using the Bioinformatics Institute's (BII) Online Sample Size Estimator (http://osse.bii.a-star.edu.sg/). Using a case-control design, based on the lowest minor allele frequency (MAF) for SNP rs486907; we based these estimates on the MAF for r […]

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