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OxyBS specifications


Unique identifier OMICS_11512
Name OxyBS
Software type Package/Module
Interface Command line interface
Restrictions to use None
Output data The output is a user-friendly array containing estimates of 5C, 5mC, and 5hmC for each CpG on the array.
Biological technology Illumina
Operating system Unix/Linux, Mac OS, Windows
Programming languages R
Computer skills Advanced
Version 1.5
Stability Stable
Maintained Yes




No version available



  • person_outline Andres Houseman <>

Publication for OxyBS

OxyBS citation


5 Hydroxymethylcytosine localizes to enhancer elements and is associated with survival in glioblastoma patients

PMCID: 5133638
PMID: 27886174
DOI: 10.1038/ncomms13177

[…] the characterization of 5 mc and 5 hmc levels from paired bs and oxbs 450 k assays in thirty glioblastomas. to effectively analyze and interpret this data, we develop and apply a novel algorithm, oxybs, and produce the first epigenome-wide characterization of 5 hmc in glioblastoma. we demonstrate that the glioblastoma genome is globally depleted of 5 hmc and its distribution is dependent […]

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OxyBS institution(s)
School of Biological and Population Health Sciences, College of Public Health and Human Sciences, Oregon State University, Corvallis, OR, USA; Department of Pharmacology and Toxicology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA; Department of Epidemiology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA
OxyBS funding source(s)
This work has been supported by the National Institutes of Health [grant numbers R01 MH094609, P20GM104416/8189].

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