P2CS statistics

Tool stats & trends

Looking to identify usage trends or leading experts?


P2CS specifications


Unique identifier OMICS_06260
Name P2CS
Restrictions to use None
Maintained Yes

Publications for P2CS

P2CS citations


Phyletic Distribution and Lineage Specific Domain Architectures of Archaeal Two Component Signal Transduction Systems

J Bacteriol
PMCID: 5847659
PMID: 29263101
DOI: 10.1128/JB.00681-17

[…] omain assignments from the NCBI's CDD (). These lists of RRs were combined and sorted according to their domain architectures. The HK and RR counts obtained were checked against those in the MiST and P2CS databases (, ), and most discrepancies (caused largely by different counting strategies) have been reconciled. No attempt was made to identify potentially missed and/or untranslated HKs or RRs (s […]


Transcriptional changes when Myxococcus xanthus preys on Escherichia coli suggest myxobacterial predators are constitutively toxic but regulate their feeding

Microb Genom
PMCID: 5857379
PMID: 29345219
DOI: 10.1099/mgen.0.000152

[…] coding sequence. Also included were genomic islands as predicted by Island Viewer 3.0 [], secondary metabolite gene clusters as predicted by antiSMASH 4.0 [], and signalling proteins as predicted by P2CS and P2TF []. […]


Chemotaxis without Conventional Two Component System, Based on Cell Polarity and Aerobic Conditions in Helicity Switching Swimming of Spiroplasma eriocheiris

Front Microbiol
PMCID: 5289999
PMID: 28217108
DOI: 10.3389/fmicb.2017.00058

[…] in and if the identity is greater or equal to 50%.The TCSs were predicted using both homology search and domain analysis. The homology search was performed against the Prokaryotic 2-Component System (P2CS) database (Barakat et al., ) through BlastP with the E < 1E-5. The computational domain analysis was performed using the method described in Song et al. (). Briefly, all the histidine kinases (HK […]


The essential genome of Streptococcus agalactiae

BMC Genomics
PMCID: 4881062
PMID: 27229469
DOI: 10.1186/s12864-016-2741-z

[…] es that encode known transcription factors, transcription factor binding sites, or RNA-based signal transduction mechanisms []. We also assessed the fitness of two-component system genes predicted by P2CS [] (Additional file : Dataset S2).Figure  illustrates representative examples of essential and nonessential genes involved in signal transduction. Figure  highlights transcription factor- and RNA […]


Genome wide survey of two component signal transduction systems in the plant growth promoting bacterium Azospirillum

BMC Genomics
PMCID: 4618731
PMID: 26489830
DOI: 10.1186/s12864-015-1962-x

[…] General features of Azospirillum TCS proteins retrieved from the P2CS database and the Mage platform are summarized in Table . The complete genomes chosen for this analysis include those of: (i) Azospirillum sp. B510, a strain isolated from disinfected rice stems i […]


Genome wide analysis of myxobacterial two component systems: genome relatedness and evolutionary changes

BMC Genomics
PMCID: 4603909
PMID: 26463047
DOI: 10.1186/s12864-015-2018-y

[…] Eight myxobacterial genomes (Mx, Mf, Sc, Ho, AF, AK, Ad1 and AdC) and that of Bb are included within the latest version of the P2CS (Prokaryotic 2-Component Systems) database, available at www.p2cs.org [, ], which provides an automated and consistent pipeline for the identification and annotation of TCS genes. The same catego […]


Looking to check out a full list of citations?

P2CS institution(s)
CEA, IBEB, Lab Ecol Microb Rhizosphere and Environ Extrem, Saint-Paul-lez-Durance, France; CNRS, UMR 7265 Biol Veget & Microbiol Environ, Saint-Paul-lez-Durance, France; Aix Marseille Université, BVME, Marseille, France; Institute of Biological, Environmental and Rural Sciences, Aberystwyth University, Ceredigion, UK

P2CS reviews

star_border star_border star_border star_border star_border
star star star star star

Be the first to review P2CS