[email protected] specifications


Unique identifier OMICS_30151
Name [email protected]
Alternative name PAGen (Promoter Analysis of Genome)
Interface Web user interface
Restrictions to use None
Computer skills Basic
Maintained No


  • Primates
    • Homo sapiens
  • Rodents
    • Mus musculus


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Publication for [email protected]


Single step doxorubicin selected cancer cells overexpress the ABCG2 drug transporter through epigenetic changes

Br J Cancer
PMCID: 2386965
PMID: 18382425
DOI: 10.1038/sj.bjc.6604334

[…] not a substrate for ABCC4 (), and ABCC4 did not confer resistance to doxorubicin (). Thus, this transporter is unlikely to be associated with drug resistance in the single-step-selected clones. Using [email protected] (www.uic.edu/pharmacy/depts/pmpcpd/pagen/), we found that there are 11 predicted transcription factors that have binding sites on the promoters of both ABCG2 and ABCC4 (). Thus, it is possib […]

[email protected] institution(s)
Departments of Biochemistry and Molecular Genetics, Medicine, Microbiology and Immunology, University of Illinois at Chicago, Chicago, IL, USA; Biopharmaceutical Sciences and Cancer Center, University of Illinois at Chicago, Chicago, IL, USA
[email protected] funding source(s)
Supported in part by NCI, National Institutes of Health Grants CA40570 and CA30103, by Department of Defense Grant DAMD17-02-1-0412, and by the University of Illinois at Chicago.

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