Offers a way to facilitate the establishment of family relationships between all known protein sequences. PairsDB aims to assign functions to novel proteins and to identify conserved parts in the protein sequences. It allows exploration of protein sequences and their similarity relationships. The database is able to report distant neighbours and display query-anchored stacked alignments. It can be useful for determination of orthologous genes in completely sequenced genomes.
MRC Functional Genetics Unit, University of Oxford, UK; Institute of Biotechnology, University of Helsinki, Finland; Center for Scientific Computing (CSC), Espoo, University of Helsinki, Finland; Department of Biological and Environmental Sciences, Division of Genetics, University of Helsinki, Finland
PairsDB funding source(s)
Supported by the Academy of Finland (grant 1102273) and the EMBRACE project, which is funded by the European Commission within its FP6 Programme, under the thematic area ‘Life sciences, genomics and biotechnology for health’, contract number LHSG-CT- 2004-512092.