The patch clamp technique permits high-resolution recording of the ionic currents flowing through a cell's plasma membrane. In different configurations, this technique has allowed experimenters to record and manipulate the currents that flow either through single ion channels or those that flow across the whole plasma membrane.
Finds dynamic changes in pixel intensity between image frames. MUSCLEMOTION expresses the output as a relative measure of movement during muscle contraction and relaxation. It can be employed for multiparameter recording conditions and experimental settings using transmitted light microscopy, fluorescent membrane labeling, fluorescent beads embedded in soft substrates or patch clamp video recordings.
Achieves hard real-time data acquisition and closed-loop control in biological experiments. RTXI is based on a Real-Time Operating System (RTOS) that modifies the operating system's native kernel architecture. It allows users to move developed and tested modules, algorithms, and entire closed-loop protocols from one computer to another without significant overhead. The tool is compatible with a wide range of experimentation hardware.
Offers a platform intending to simplify the manipulation of oscillations, spikes, and neural signals. OpenElectrophy is a python package providing support features for the Neo software. The application can be run as both a graphic interface and a command-line application and proposes additional functions dedicated to storage, fast wavelet scalogram plotting or exploration of data coupled to a visualization tool.
Offers an assortment of tools allowing users to perform data analysis, data acquisition and simulation of electrophysiological data. NeuroMatic provides an extensible toolkit that have to be run through the Igor platform software. It provides a wide range of functionalities including triggered stimulation, spike detection, simulations of stochastic synaptic transmission as well as voltage and current clamp.