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PathCards specifications

Information


Unique identifier OMICS_07645
Name PathCards
Restrictions to use None
Community driven No
Data access Browse
User data submission Not allowed
Maintained Yes

Taxon


  • Primates
    • Homo sapiens

Maintainer


  • person_outline Frida Belinky

Publication for PathCards

PathCards citations

 (4)
library_books

Rational confederation of genes and diseases: NGS interpretation via GeneCards, MalaCards and VarElect

2017
Biomed Eng Online
PMCID: 5568599
PMID: 28830434
DOI: 10.1186/s12938-017-0359-2

[…] relatedness scheme, which includes aliases, disease families, related diseases and disease SuperPaths (Fig. ). SuperPaths are integrated biological pathways from 12 information sources, shown in the PathCards database, a member of the GeneCards suite []. This hierarchical disease relatedness scheme constitutes a major MalaCards strength for NGS interpretation, allowing one to gradually augment th […]

library_books

Common shared genetic variation behind decreased risk of breast cancer in celiac disease

2017
Sci Rep
PMCID: 5517429
PMID: 28725034
DOI: 10.1038/s41598-017-06287-9

[…] sidered for cancer immunotherapy . ILI12A loci selected through genetic population factors have been associated with celiac disease and other autoimmune diseases. A query in a pathway catalog (http://pathcards.genecards.org; accessed on November 15, 2016) showed that other significantly prioritized genes (SEMA7A, ITGA4, IL18RAP, CD24, TAGA, TNFRSF, ZFP36L1) are classified on immune-related signali […]

library_books

GeneAnalytics Pathway Analysis and Genetic Overlap among Autism Spectrum Disorder, Bipolar Disorder and Schizophrenia

2017
Int J Mol Sci
PMCID: 5372543
PMID: 28264500
DOI: 10.3390/ijms18030527

[…] sses, molecular functions, phenotypes, tissues and cells, diseases and compounds affected by overlapping neuropsychiatric genes.GeneAnalytics is powered by GeneCards, LifeMap Discovery, MalaCards and PathCards, which combine >100 archived data sources []. The databases contain gene lists for tissues and cells, diseases, phenotypes pathways and compounds curated from published literature reports to […]

library_books

Neurogenin 3 is regulated by neurotrophic tyrosine kinase receptor type 2 (TRKB) signaling in the adult human exocrine pancreas

2016
PMCID: 5034529
PMID: 27659207
DOI: 10.1186/s12964-016-0146-x

[…] ty analysis was done using CummeRbund analysis software []. The neurotrophin pathways list is comprised of 320 genes directly involved in neurotrophin signaling or downstream targets curated from the PathCards database (Weizmann Institute of Science, pathcards.genecards.org), SA Biosciences RT2 array list (sabiosciences.com) and the Broad Institute Molecular Signatures Database (MSigDB, broadinsti […]

Citations

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PathCards institution(s)
Department of Molecular Genetics, Weizmann Institute of Science, Rehovot, Israel
PathCards funding source(s)
Supported by grants from LifeMap Sciences Inc. California (USA) and the SysKid—EU FP7 project (number 241544) and the Crown Human Genome Center at the Weizmann Institute of Science.

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