PATHiWAYS statistics

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Signaling pathways

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Associated diseases

PATHiWAYS specifications

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Information

Unique identifier	OMICS_07766
Name	PATHiWAYS
Interface	Web user interface
Restrictions to use	None
Input data	Gene expression
Output data	Pathway activity
Programming languages	Java, Javascript
License	GNU General Public License version 2.0
Computer skills	Basic
Stability	Stable
Maintained	Yes

Taxon

Primates
- Homo sapiens
Rodents
- Mus musculus

Publications for PATHiWAYS

Understanding disease mechanisms with models of signaling pathway activities.

2014 BMC Syst Biol

PMCID: 4213475

PMID: 25344409

DOI: 10.1186/s12918-014-0121-3

Inferring the functional effect of gene expression changes in signaling pathways.

2013 Nucleic Acids Res

PMCID: 3692130

PMID: 23748960

DOI: 10.1093/nar/gkt451

PATHiWAYS in publication

Using activation status of signaling pathways as mechanism based biomarkers to predict drug sensitivity

PMCID: 4683444

PMID: 26678097

DOI: 10.1038/srep18494

[…] agreement between the change of phosphorylation status of the proteins measured that belong to a circuit selected by the predictor and the change in signaling obtained upon the application of the pathiways tool for this circuit. some apparent contradictions can easily be explained by the topology of the circuits. for example, in the case of insulin signaling pathway, pdpk1 shows […]

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PATHiWAYS institution(s)

Computational Genomics Department, CIPF, Valencia, Spain

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