PathScan statistics

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PathScan specifications


Unique identifier OMICS_05320
Name PathScan
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Programming languages Perl
Computer skills Advanced
Stability No
Maintained No


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Publication for PathScan

PathScan in publications

PMCID: 5932570
PMID: 29722156
DOI: 10.14814/phy2.13687

[…] phosphokinase antibody array, as previously reported (umemura et al. ). hcfs were maintained at 0 mmhg (ap) or 200 mmhg (hp conditions) for 60 min. microarray experiments were carried out using the pathscan signaling antibody array kit (cell signaling) according to the manufacturer's instructions. signal intensities were quantified using atto cs analyzer 4 software (atto, tokyo, japan)., […]

PMCID: 5915732
PMID: 29691342
DOI: 10.1128/mBio.00682-18

[…] (rtks) activated through these pathways. for these studies, cd34+ hpcs were transduced with an adenovirus vector expressing ul7 (ad-ul7) followed by analysis of rtks 24 h posttransduction using the pathscan rtk signaling antibody array that detects the phosphorylation of tyrosine residues in 28 rtks and activation of 11 signaling nodes. analysis of the results revealed a 5.8-fold increase […]

PMCID: 5862986
PMID: 29563546
DOI: 10.1038/s41598-018-23277-7

[…] and protease inhibitor cocktail (sigma-aldrich, p8340) and the lysate supernatants diluted to 1 mg/ml protein. the phosphorylation status of 150 µg lysate proteins was determined using pathscan rtk signalling arrays (cell signalling technology, danvers, ma). chemiluminescent signals of all arrays were detected on x-ray films, and the pixel intensities were measured using imagej […]

PMCID: 5873869
PMID: 29568964
DOI: 10.3892/ijo.2018.4325

[…] 7302), p-p38 mapk (thr180/tyr182) (cat. no. 7946), p-p44/42 mapk (thr202/tyr204) (cat. no. 7177), and p-akt (thr308) (cat. no. 7252) assays were performed according to the manufacturer's protocols (pathscan sandwich elisa kits; cell signaling technology, inc.). in total, ~1×107 u-2 os cells/ml were plated on 24-well plates and treated with 0, 20 or 40 μm of hmj-30 or with specific protein […]

PMCID: 5839064
PMID: 29510727
DOI: 10.1186/s13046-018-0715-5

[…] rna (sirna) was employed to analyze the role of eef1d in osteosarcoma cell proliferation and cell cycle progression. the host signaling pathways affected by eef1d knockdown were detected using pathscan® intracellular signaling array kit., the expression of eef1d was found to be up-regulated in human osteosarcoma tissues and cell lines. its expression was positively correlated with enneking […]

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PathScan institution(s)
The Genome Institute, Washington University, St Louis, MO, USA

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