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Pathway Flow specifications


Unique identifier OMICS_16358
Name Pathway Flow
Interface Web user interface
Restrictions to use None
Input data A list of BioCyc IDs, the pathway network, the response groups to consider.
Computer skills Basic
Stability No
Maintained No


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Publication for Pathway Flow

Pathway Flow citations


Propofol induces a metabolic switch to glycolysis and cell death in a mitochondrial electron transport chain dependent manner

PLoS One
PMCID: 5813975
PMID: 29447230
DOI: 10.1371/journal.pone.0192796

[…] itochondrial membrane potential and an impairment of OXPHOS. In this study, propofol treatment promoted caspase-9 and caspase-3/7 activation. These data indicate that propofol activates the apoptosis pathway. Flow cytometry analysis indicated that the treatment of cells with propofol concentrations greater than 50 μM for 12 h also resulted in LDH release and increased the PI+/annexin V− cell popul […]


Evaluation of a type 2 diabetes prevention program using a commercial weight management provider for non diabetic hyperglycemic patients referred by primary care in the UK

PMCID: 5706489
PMID: 29225891
DOI: 10.1136/bmjdrc-2017-000418
call_split See protocol

[…] was between 10% and 30%; in order to treat 109 patients, a minimum of 120–142 patients needed to be referred to the program, but the actual number of patients referred was 166 patients.. The referral pathway flow diagram illustrates the referral pathway, recruitment and adherence of patients (). […]


PSFC: a Pathway Signal Flow Calculator App for Cytoscape

PMCID: 4706054
PMID: 26834984
DOI: 10.5256/f1000research.7203.r9853

[…] er similar software, PSFC stands out with a wide set of rules and options for signal propagation, which makes it possible to use the app for the majority algorithms that could possibly be applied for pathway flow calculations in different biological contexts. It is, thus, not constrained with preset algorithm design, but allows users to apply their own algorithms. Thus, PSCF can be used in routine […]


Veno occlusive disease nurse management: development of a dynamic monitoring tool by the GITMO nursing group

PMCID: 4990055
PMID: 27594906
DOI: 10.3332/ecancer.2016.661

[…] tured meetings.The NEP evaluated the results and identified the key points for the development of the tool to assess and monitor patients throughout their transplant journey. Then, the NEP produced a pathway flow chart. […]


Cost Effectiveness of Including a Nurse Specialist in the Treatment of Urinary Incontinence in Primary Care in the Netherlands

PLoS One
PMCID: 4591337
PMID: 26426124
DOI: 10.1371/journal.pone.0138225

[…] not actively followed for improvement of symptoms; or 3) self-management, where the patient is neither actively treated for cure nor treated for containment.Patients who enter the treatment for cure pathway flow into a Markov process where they will move to one of three possible health states (): 1) incontinent; 2) improvement, where patients experience at least 50% fewer incontinence episodes; a […]


Time course human urine proteomics in space flight simulation experiments

BMC Genomics
PMCID: 4303941
PMID: 25563515
DOI: 10.1186/1471-2164-15-S12-S2

[…] so-called 'spots' collect co-expressed proteins representing regulatory modes associated with distinct biological processes which can be identified using previous knowledge by applying enrichment or pathway flow analysis. In total we identified about ten different modes of protein abundance. Application of different methods of spot selection (e.g. using overexpression, correlation or K-means clus […]


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Pathway Flow institution(s)
Bioinformatics and Computational Biology, Electrical and Computer Engineering Department, Iowa State University, Ames, IA, USA
Pathway Flow funding source(s)
This work was supported by the National Science Foundation programs DBI (grant number 0604755) and EEC (grant number 0813570).

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