Pathway Hunter Tool specifications

Information


Unique identifier OMICS_20281
Name Pathway Hunter Tool
Alternative name PHT
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Maintainers


  • person_outline asadrahman <>
  • person_outline Dietmar Schomburg <>

Publications for Pathway Hunter Tool

Pathway Hunter Tool in publications

 (7)
PMCID: 5766603
PMID: 29330441
DOI: 10.1038/s41467-017-02362-x

[…] native or de novo enzymatic functions to assemble pathways toward targeted chemicals. this is an area of research with significant prior work. network-based path finding methods such as pathcomp, pathway hunter tool, and metaroute identify linear pathways from a single source to one target molecule. these methods rely on heuristics such as substrate-product similarity, atom transitions, […]

PMCID: 5851934
PMID: 29552648
DOI: 10.1016/j.synbio.2017.11.002

[…] on the underlying representation of the metabolic network (see d). breadth-first search (bfs) is a widely used algorithm to find the k-shortest paths in a loopless unweighted graph as applied in the pathway hunter tool . as many preprocessing steps assign weights to a graph based on thermodynamics or other criteria, the search requires algorithms such as yen's k-shortest path algorithm […]

PMCID: 5602787
PMID: 29086092
DOI: 10.1186/s13321-017-0239-6

[…] different compounds and is calculated by dividing the total number of structural features shared between the two compounds by the total number of structural features contained in both compounds. in pathway hunter tool (pht) [], chemical fingerprints are included in the metabolite mapping scoring function, which is calculated by summing the calculated chemical similarity score and percentage […]

PMCID: 3143899
PMID: 21884622
DOI: 10.1186/2043-9113-1-2

[…] is the biological and biochemical interpretation of identified putative marker candidates by means of mining the most likely pathways. in metabolomics, various explorer tools such as cpath, pathway hunter tool (public) or ingenuity pathway analysis and metacore (commercial) are available to visualize, map and reconstruct a spectrum of possible pathways between relevant metabolites […]

PMCID: 2791103
PMID: 19874610
DOI: 10.1186/1752-0509-3-103

[…] atp., there have been attempts to avoid the problem of assigning a list of side metabolites altogether in pathway analysis tasks. rahman et al. utilized information on metabolite structures in pathway hunter tool (pht) []. in pht, metabolite structural similarity is first used to identify reactant pairs in reactions which resemble each other most. path finding is then performed on a graph […]


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Pathway Hunter Tool institution(s)
Cologne University Bioinformatics Center, CUBIC, Koeln, Germany; Institute for Biochemistry, Koeln, Germany
Pathway Hunter Tool funding source(s)
Supported by the German Federal Ministry for Education and Research (BMBF).

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