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Pathway interactive visualization tooL PiiL


Allows direct comparison and testing specific hypotheses in model organisms for which pathway and expression network data exists. PiiL is an integrated DNAm and expression pathway browser. It was designed to explore and understand the effect of DNAm operating on individual CpG sites on overall expression patterns and transcriptional networks. It implements a multi-level paradigm, which allows examining global changes in expression, comparisons between multiple sample groupings, play-back of time series.

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PiiL classification

PiiL specifications

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Graphical user interface
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Unix/Linux, Mac OS, Windows
GNU General Public License version 3.0

PiiL distribution


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PiiL support


  • Manfred Grabherr <>


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Biology, Uppsala University, Uppsala, Sweden; Department of Medical Biochemistry and Microbiology/BILS, Genomics, Uppsala University, Uppsala, Sweden; Department of Plant Physiology, Umeå University, Umeå, Sweden; Institute of Computer Science, Polish Academy of Sciences, Warsaw, Poland

Funding source(s)

Supported by a FORMAS grant, an eSSENCE grant and in part by a grant from the Polish National Science Centre [DEC-2015/16/W/NZ2/00314].

Link to literature

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