PathwayOracle statistics

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Citations per year

Number of citations per year for the bioinformatics software tool PathwayOracle

Tool usage distribution map

This map represents all the scientific publications referring to PathwayOracle per scientific context
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PathwayOracle specifications


Unique identifier OMICS_28306
Name PathwayOracle
Alternative name PathwayOracle Toolkit
Software type Toolkit/Suite
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages Python
License GNU General Public License version 3.0
Computer skills Advanced
Version 1.0.5
Stability Stable
Numpy, Matplotlib, PIL
Source code URL
Maintained Yes


No version available


  • person_outline Derek Ruths
  • person_outline Luay Nakhleh
  • person_outline Prahlad T Ram

Publication for PathwayOracle

PathwayOracle citation


Kinome siRNA phosphoproteomic screen identifies networks regulating AKT signaling

PMCID: 3175328
PMID: 21666717
DOI: 10.1038/onc.2011.164

[…] tal to 49). The sequences of these siRNA are shown in .The fifteen siRNAs that increased pAKT could target negative regulators acting upstream of AKT or potentially components of feedback loops. With PathwayOracle (; ), we reconstructed a directed signaling network based on published literature (PubMed) to identify possible pathways accounting for the increase in pAKT levels. Of the 15 siRNAs that […]

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PathwayOracle institution(s)
Department of Computer Science, Rice University, Houston, TX, USA; Department of System Biology, University of Texas MD Anderson Cancer Center, Houston, TX, USA
PathwayOracle funding source(s)
Supported in part by a Seed Grant awarded from the Gulf Coast Center for Computational Cancer Research, funded by John and Ann Doerr Fund for Computational Biomedicine, and in part by a Department of Defense grant BC044268.

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