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PC-TraFF specifications


Unique identifier OMICS_21957
Name PC-TraFF
Alternative names Potentially Collaborating Transcription Factor finder, PC-TraFF_Professional
Interface Web user interface
Restrictions to use None
Input data A sequence set and a PWM library.
Output data A set of significant TFBS pairs.
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline Mehmet Gultas
  • person_outline Cornelia Meckbach
  • person_outline Edgar Wingender

Additional information

http://pctraffpro.bioinf.med.uni-goettingen.de/newjob.php http://pctraffpro.bioinf.med.uni-goettingen.de/example.php

Publication for Potentially Collaborating Transcription Factor finder

PC-TraFF citation


Computational Detection of Stage Specific Transcription Factor Clusters during Heart Development

Front Genet
PMCID: 4804722
PMID: 27047536
DOI: 10.3389/fgene.2016.00033
call_split See protocol

[…] tations, a RefSeq gene can have multiple overlapping promoter regions which results in overestimation of the importance of some transcription factor binding sites (TFBSs). Thus, following the line of PC-TraFF to remove the redundancy between sequences, we filtered them regarding their TSSs (Meckbach et al., ). Consequently, we used in our analysis only those sequences which have no overlap.In this […]

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PC-TraFF institution(s)
Institute of Bioinformatics, University of Göttingen, Göttingen, Germany; Institute of Computer Science, University of Göttingen, Göttingen, Germany

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