pCLAMP protocols

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pCLAMP statistics

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pCLAMP specifications


Unique identifier OMICS_25410
Software type Toolkit/Suite
Interface Graphical user interface
Restrictions to use License purchase required
Operating system Windows
Computer skills Medium
Version 11
Stability Stable
Maintained Yes


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pCLAMP in pipeline

PMCID: 3558750
PMID: 22179109
DOI: 10.1038/nn.3004

[…] (emd chemicals, san diego, ca, usa) was used at 50 μm during recording and 100 μm for the 30 minute pre-incubation., all electrophysiology data acquisition and analysis was carried out using pclamp9 (molecular devices) software, while neuroexplorer (microbrightfield, williston, vt) was used for morphometric analysis. results are expressed as means and standard errors. the physiological […]

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pCLAMP in publications

PMCID: 5959318
DOI: 10.1126/sciadv.aat0351

[…] filled with a solution consisting of 150 mm kcl, 5 mm nacl, 5 mm mgatp, 10 mm hepes, 5 mm egta (ph 7.2). all recordings were acquired using a digidata 1322 interface, an axopatch 200b amplifier, and pclamp software (molecular devices). the data were digitally sampled at 10 khz and filtered using an eight-pole bessel analog low-pass filter at 2-khz cutoff frequency., the redox dye resazurin […]

PMCID: 5956745
PMID: 29780879
DOI: 10.1523/ENEURO.0387-17.2018

[…] μm, sigma) was added to this intracellular solution immediately before each recording session., currents were recorded at 22–26°c using an axopatch 1d or axopatch 200b amplifier and acquired using pclamp10 and a digidata 1200 interface (molecular devices). series resistance and input capacitance were read directly from the amplifier settings used to minimize the current responses to 5-mv […]

PMCID: 5958052
PMID: 29773801
DOI: 10.1038/s41467-018-04353-y

[…] (220 mosm). all recordings were performed at room temperature. we used an epc-10 patch-clamp amplifier controlled with the patchmaster software (heka). data were analyzed using the software pclamp 10.6 (molecular devices). patch pipettes were pulled to a resistance of 2–5 mω., β-cell mass was calculated from immunohistochemical stainings as the ratio of insulin-positive area to total […]

PMCID: 5955950
PMID: 29769580
DOI: 10.1038/s41598-018-25940-5

[…] 140 kcl, 13.4 nacl, 0.5 cacl2, 1 mgcl2, 5 egta, 10 hepes, and 3 mg-atp, 0.3 na3-gtp (280–285 mosm, ph 7.2). signals were acquired (sampling 10 khz, low-pass filtered 2 khz) with digidata-1440a using pclamp-v10 software (molecular devices, usa). membrane capacitance was estimated as the total charge (i.e., the current integral, qstep) mobilized in each cell by a 10 mv hyperpolarizing step […]

PMCID: 5955955
PMID: 29769701
DOI: 10.1038/s41598-018-25949-w

[…] solution as described previously,. glass pipettes (8–15 mω) were pulled using a sutter p-1000 puller and filled with internal solution. the resulting signal was then monitored and recorded using pclamp10 clampex software and pipette offsets were zeroed prior to cell contact with the pipette capacitance being compensated upon contact. subsequent signals were passed through a 10 khz low-pass […]

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