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pcot2

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Represents a permutation-based method for investigating changes in the activity of multigene networks. pcot2 is an effective multivariate statistical procedure which allows to assess the correlation between a subspace defined by a group of genes and a binary phenotype. It works with inter-gene correlation information in order to discover significant alterations in gene network activities. This tool can be used to perform about two-sample comparisons.

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pcot2 classification

pcot2 specifications

Software type:
Package/Module
Restrictions to use:
None
Programming languages:
R
Computer skills:
Advanced
Stability:
Stable
Interface:
Command line interface
Operating system:
Unix/Linux, Mac OS, Windows
License:
GNU General Public License version 2.0
Version:
1.44.0
Maintained:
Yes

pcot2 distribution

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pcot2 support

Documentation

Maintainer

  • Peter J. Park <>

Credits

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Publications

Institution(s)

Department of Cardiology, Children’s Hospital Boston, Boston, MA, USA; Informatics Program, Children’s Hospital Boston, Boston, MA, USA; Harvard-Partners Center for Genetics and Genomics, Boston, MA, USA

Funding source(s)

Supported by the grants from the Specialized Centers of Clinically Oriented Research in Pediatric Heart Development and Disease, the National Institute of General Medical Sciences and the NIH Roadmap for Medical Research Grant U54LM008748.

Link to literature

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