Tool stats & trends
Looking to identify usage trends or leading experts?
|Restrictions to use||None|
- Homo sapiens
Publication for PDGene
Discovery and functional prioritization of Parkinson’s disease candidate genes from large scale whole exome sequencing
[…] p PD, next to the identified LoF variants with assumed high penetrance, we searched for GWAS loci within 1 Mb upstream and downstream of the gene of interest using the recent PD meta-analysis through pdgene.org . Significant associations and suggestive p values < 1e-4 were considered. To understand the underlying linkage disequilibrium structure, LocusZoom  was applied to visualize the Europea […]
Enrichment of risk SNPs in regulatory regions implicate diverse tissues in Parkinson’s disease etiology
[…] Twenty-six index SNPs associated with PD were downloaded from http://www.pdgene.org/top_results. Five SNPs were removed from further analysis. Rs17649553 was removed because it was in an assembly exception. Rs11060180, rs34311866, rs356182 and rs62120679 were removed becau […]
Large scale meta analysis of genome wide association data identifies six new risk loci for Parkinson’s disease
[…] niMac (http://genome.sph.umich.edu/wiki/Minimac) 1000 Genomes haplotypes (http://www.sph.umich.edu/csg/abecasis/MaCH/download/) Summary statistics of this study have been made available at http://www.pdgene.org (Note to the editor/reviewers: Summary statistics of the discovery, conditional and replication phase of this study will be made available to the community at the listed URL upon publicatio […]
Towards a pathway definition of Parkinson’s disease: a complex disorder with links to cancer, diabetes and inflammation
[…] ResNet database, respectively, that was obtained via NetAffx (http://www.affymetrix.com/analysis/index.affx). Thirty-one priority genes have been previously designated PD candidate genes (http://www.pdgene.org/) (SI_Table_1f), and it is worth noting that 33 are considered AD candidate genes as well (SI_Table_1g) with HSPA1A, HSPA1B, HTR2A, KCNJ6, SLC6A3, SNCA, SNCG, TF and UCHL1 being present in […]
Looking to check out a full list of citations?
Be the first to review PDGene