Provides access to a comprehensive set of putative and native protein-drug interactions in the structural human proteome. The structural human proteome includes about 10,000 human and human-like (with high sequence similarity to human proteins) proteins with known 3-D structures. The database includes data for popular, FDA-approved drugs. The corresponding protein-drug interactions were generated with three predictors, and were collected from and linked with three related databases of known protein-drug interactions.
Department of Electrical and Computer Engineering, University of Alberta, Edmonton, Canada
PDID funding source(s)
This work was supported by the Natural Sciences and Engineering Research Council (NSERC) Canada [Discovery grant 298328]; the National Natural Science Foundation of China [31050110432, 31150110577, 11101226, and 11301286]; and the National Institute of Health [LM011986].