Unlock your biological data
Chromatin immunoprecipitation coupled with high-throughput sequencing (ChIP-seq) has become standard technology to investigate genome wide binding sites of transcription factors (TFs). In order to analyze these DNA binding sites to determine their potential regulatory functions, proximal genes/transcripts and regulatory elements are considered to annotate these loci. Several applications were developed for annotating ChIP-seq data.
(Yu et al., 2015) ChIPseeker: an R/Bioconductor package for ChIP peak annotation, comparison and visualization. Bioinformatics.