Protocols

PeakHeights specifications

Information


Unique identifier OMICS_10359
Name PeakHeights
Software type Package/Module
Interface Graphical user interface
Restrictions to use None
Operating system Windows
Computer skills Medium
Stability Stable
Requirements
Net framework
Maintained Yes

Versioning


No version available

Maintainer


  • person_outline Ian M. Carr

PeakHeights citations

 (2)
call_split

A novel germline POLE mutation causes an early onset cancer prone syndrome mimicking constitutional mismatch repair deficiency

2016
PMCID: 5243902
PMID: 27573199
DOI: 10.1007/s10689-016-9925-1
call_split See protocol

[…] blood lymphocytes. Subsequently, PCR products were separated by capillary electrophoresis on an ABI3130 genetic analyzer. gMSI ratios are calculated using PeakHeight-Software (http://dna.leeds.ac.uk/peakheights/) and are compared to laboratory-specific threshold ratios, which are defined as the mean + 3-times standard deviation (SD) of 80–90 control DNAs. Germline microsatellite stability is stat […]

library_books

Influences of COMT and 5 HTTLPR Polymorphisms on Cognitive Flexibility in Healthy Women: Inhibition of Prepotent Responses and Memory Updating

2014
PLoS One
PMCID: 3896383
PMID: 24465579
DOI: 10.1371/journal.pone.0085506

[…] or the computer-assisted calling of the 5-HTTLPR s and l alleles, size bins of 131.2±0.5 nt and 175.2±0.5 nt, respectively, were used. Further, a peak height threshold of 250 rfu was defined (typical peakheights obtained for both homozygous states were at about 8500 rfu and those found for heterozygotes fell in the range of 6500–8300 rfu). […]

PeakHeights institution(s)
Leeds Institute of Molecular Medicine, Wellcome Trust Brenner Building, University of Leeds, St James's University Hospital, Beckett Street, Leeds, UK

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