bookmark PepComposer star_border star_border star_border star_border star_border star star star star star (1) A pipeline for the computational design of peptides binding to a given protein surface. PepComposer only requires the target protein structure and an approximate definition of the binding site as input. It first retrieves a set of peptide backbone scaffolds from monomeric proteins that harbor the same backbone arrangement as the binding site of the protein of interest. Next, it designs optimal sequences for the identified peptide scaffolds. The method is fully automatic and available as a web server.