Peptide prediction & design tools

Over the past few decades, scientific research has been focused on developing peptide based therapies to treat various diseases. Owing to their immense therapeutic importance, peptides have been curated from literature and stored in form of databases. Also, a number of…

Peptide prediction steps

AntiCP
Web

AntiCP

A web-based prediction server for Anticancer peptides. AntiCP would be helpful…

A web-based prediction server for Anticancer peptides. AntiCP would be helpful in: (i) predicting minimum mutations required for improving anticancer potency; (ii) virtual screening of peptides for…

PeptideAtlas
Dataset

PeptideAtlas

Annotates eukaryotic genomes with peptide sequences obtained from mass…

Annotates eukaryotic genomes with peptide sequences obtained from mass spectrometry (MS) experiments. PeptideAtlas is a compendium of observations of peptides and associated annotations, based on a…

ArachnoServer
Dataset

ArachnoServer

A manually curated database containing information on the sequence,…

A manually curated database containing information on the sequence, three-dimensional structure, and biological activity of protein toxins derived from spider venom.

Norine
Dataset

Norine

A knowledgebase dedicated to non-ribosomal peptides (NRPs). These secondary…

A knowledgebase dedicated to non-ribosomal peptides (NRPs). These secondary metabolites, produced by bacteria and fungi, harbor diverse interesting biological activities (such as antibiotic,…

ATDB
Dataset

ATDB Animal Toxin DataBase

It mainly focuses on construct a globe-scale animal toxin-channel interaction…

It mainly focuses on construct a globe-scale animal toxin-channel interaction network based on literatures and database annotations.

AHTPDB
Dataset

AHTPDB

A manually curated database of experimentally validated antihypertensive…

A manually curated database of experimentally validated antihypertensive peptides. Information pertaining to peptides with antihypertensive activity was collected from research articles and from…

EPI-Peptide…
Desktop

EPI-Peptide Designer

A computational method to generate libraries of peptide ligands or paratope…

A computational method to generate libraries of peptide ligands or paratope mimetics based on the epitope-paratope interaction (EPI) patterns and on a target epitope input sequence. EPI-Peptide…

AVP-IC50Pred
Algorithm

AVP-IC50Pred Antiviral peptide IC50 predictor

A regression-based algorithm to predict the antiviral activity in terms of IC50…

A regression-based algorithm to predict the antiviral activity in terms of IC50 values (μM). AVP-IC50Pred is developed using peptides with quantitative and experimentally proven antiviral activity…

iACP
Web

iACP Anticancer Peptides

A web-server for identifying whether a peptide belongs to anticancer or…

A web-server for identifying whether a peptide belongs to anticancer or non-anticancer purely based on its sequence information alone. iACP uses the wrapper-type feature selection technique to seek…

Hemolytik
Dataset

Hemolytik

A manually curated database of experimentally validated Hemolytic and…

A manually curated database of experimentally validated Hemolytic and Non-hemolytic peptides.

Dover Analyzer
Desktop

Dover Analyzer

A wizard like application that takes collections of databases annotated in…

A wizard like application that takes collections of databases annotated in FASTA format and guides the user through a few steps to compute the overlap, diversity and redundant or non-redundant sets…

SEMBA
Desktop

SEMBA

A program for analyzing the binding affinity of amyloid proteins. SEMBA uses an…

A program for analyzing the binding affinity of amyloid proteins. SEMBA uses an energy function that computes the Lennard-Jones, Coulomb, and solvation energies to determine the effect of a mutation…

WALTZ-DB
Dataset

WALTZ-DB

Accurate prediction of amyloid-forming amino acid sequences remains an…

Accurate prediction of amyloid-forming amino acid sequences remains an important challenge. WALTZ-DB is an online database that provides open access to the largest set of experimentally characterised…

Peptide Design
Desktop

Peptide Design

An efficient graph-based algorithm to predict peptides with the highest…

An efficient graph-based algorithm to predict peptides with the highest biological activity for machine learning predictors using the GS kernel. Combined with a multi-target model, it can be used to…

ActiveSeqAnalyz…
Desktop

ActiveSeqAnalyzerTN

Allows extraction of optimal sequence related to biological activity.

Allows extraction of optimal sequence related to biological activity.

EROP-Moscow
Dataset

EROP-Moscow Endogenous Regulatory OligoPeptides-Moscow

Gathers and dispatches information about natural regulatory oligopeptides and…

Gathers and dispatches information about natural regulatory oligopeptides and their structurally homologous families. EROP compiles each natural oligopeptide by using an entry including its physical,…

ConoServer
Dataset

ConoServer

A database specializing in the sequence and structures of conopeptides, which…

A database specializing in the sequence and structures of conopeptides, which are peptides expressed by carnivorous marine cone snails.

AntiAngioPred
Web

AntiAngioPred

A user-friendly web server for the prediction of anti-angiogenic peptides. A…

A user-friendly web server for the prediction of anti-angiogenic peptides. A user can submit the peptide sequence in the ‘Predict’ module of the web server and can predict whether his/her peptide…

HemoPI
Desktop
Web
Mobile

HemoPI

A web server for computing hemolytic potency of peptides. HemoPI facilitates…

A web server for computing hemolytic potency of peptides. HemoPI facilitates the design of therapeutic peptides. It allows user to predict hemolytic, hemotoxic or red blood cell lysing potential of a…

Arabidopsis…
Dataset

Arabidopsis Unannotated Secreted Peptide Database

This is a searchable database of bioinformatic predictions of putative…

This is a searchable database of bioinformatic predictions of putative intergenic unannotated secreted peptides from Arabidopsis thaliana.

ProPepper
Dataset

ProPepper

A database of cereal prolamin epitopes, peptides and proteins for expert users…

A database of cereal prolamin epitopes, peptides and proteins for expert users that are dealing with protein chemistry, proteomics and mass spectrometry, method developments and related applications…

Brainpeps
Dataset

Brainpeps

Collects and stores blood–brain barrier (BBB) transport information with…

Collects and stores blood–brain barrier (BBB) transport information with positive as well as negative results. Brainpeps allows to prioritize peptide choices for evaluating different BBB responses…

HLP
Dataset

HLP

A server developed for predicting half-life of peptides in intestine like…

A server developed for predicting half-life of peptides in intestine like environment.

PeptideDB
Dataset

PeptideDB

Assembles all naturally occurring signalling peptides from animal source, which…

Assembles all naturally occurring signalling peptides from animal source, which are derived by cleavage from prepropeptide precursor proteins.

ACPP
Web
Desktop

ACPP Anti-cancer peptide predictor

An anti-cancer peptide predictor to predict and design anti-cancer peptide…

An anti-cancer peptide predictor to predict and design anti-cancer peptide effectively and reports the query protein to have apoptotic function or not. ACPP includes three different modes : (i)…

Hmrbase
Dataset

Hmrbase

A database for managing information about hormones and their receptors. Hmrbase…

A database for managing information about hormones and their receptors. Hmrbase is a highly curated database for which information has been collected from the literature and the public databases.…

ToxinPred
Desktop
Web

ToxinPred

An in silico method, which is developed to predict and design toxic/non-toxic…

An in silico method, which is developed to predict and design toxic/non-toxic peptides.

BactPepDB
Dataset

BactPepDB

A database that aims at providing an exhaustive re-annotation of all complete…

A database that aims at providing an exhaustive re-annotation of all complete prokaryotic genomes-chromosomal and plasmid DNA-available in RefSeq for coding sequences ranging between 10 and 80 amino…

ParaPep
Dataset

ParaPep

A repository of antiparasitic peptides, which provides comprehensive…

A repository of antiparasitic peptides, which provides comprehensive information related to experimentally validated antiparasitic peptide sequences and their structures.

SPdb
Dataset

SPdb

A repository of experimentally determined and computationally predicted signal…

A repository of experimentally determined and computationally predicted signal peptides.

iAMP-2L
Web

iAMP-2L

A web application for identifying AMPs and their functional types. iAMP-2L is a…

A web application for identifying AMPs and their functional types. iAMP-2L is a multi-label classifier based on the pseudo amino acid composition (PseAAC) and fuzzy K-nearest neighbor (FKNN)…

BIOPEP
Web

BIOPEP

Contains a database of biologically active peptide sequences and a program…

Contains a database of biologically active peptide sequences and a program enabling construction of profiles of the potential biological activity of protein fragments, calculation of quantitative…

ClassAMP
Web

ClassAMP

A prediction tool for classification of antimicrobial peptides (AMPs). ClassAMP…

A prediction tool for classification of antimicrobial peptides (AMPs). ClassAMP uses random forests (RFs) and support vector machines (SVMs) to predict the propensity of a protein sequence to have…

PEPlife
Dataset

PEPlife

A manually curated database of experimentally validated therapeutic peptides…

A manually curated database of experimentally validated therapeutic peptides and their half-lives. In this database, peptides have been collected from both published articles as well as from patents.…

BacGen
Web

BacGen

An alignment-independent method for predicting both protective antigens and…

An alignment-independent method for predicting both protective antigens and antigenic proteins in Bacteria using sequence derived information. BacGen yields performance that is comparable to or…

ACEpepDB
Dataset

ACEpepDB

The food sources available and the antihypertensive peptide sequences tailored…

The food sources available and the antihypertensive peptide sequences tailored from them by a number of ways, characterized by different methods and ACE inhibition quantitated by various assays are…

HUPD
Dataset

HUPD Human Urinary Proteome Database

The database of these datasets compiled from the urinary peptides enables the…

The database of these datasets compiled from the urinary peptides enables the diagnosis, classification, and monitoring of a wide range of diseases.

BTXpred
Web

BTXpred

Predicts bacterial toxins and its function from primary amino acid sequence…

Predicts bacterial toxins and its function from primary amino acid sequence using SVM, HMM and PSI-Blast. Bacterial toxins play a vital role to cause disease and are responsible for majority of…

NTXpred
Web

NTXpred

A method for predicting neurotoxins and classifying them based on their…

A method for predicting neurotoxins and classifying them based on their function and origin.

MHCPEP
Dataset

MHCPEP

A curated database comprising over 13 000 peptide sequences known to bind MHC…

A curated database comprising over 13 000 peptide sequences known to bind MHC molecules. Entries are compiled from published reports as well as from direct submissions of experimental data. Each…

PredSTP
Web

PredSTP

An SVM-based model to predict sequential tri-disulfide peptide (STP) toxins…

An SVM-based model to predict sequential tri-disulfide peptide (STP) toxins from peptide sequences. PredSTP can accurately identify a wide range of cystine stabilized peptide toxins directly from…

Curators for Peptide prediction

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