Generates a list of the most appropriate surrogate peptides for target proteins to be analyzed by Liquid Chromatography/Multiple Reaction Monitoring-Mass Spectrometry (LC/MRM-MS). PeptidePicker integrates information from different data sources including UniProtKB, Global Proteome Machine, NCBI's dbSNP, PRIDE, and PeptideAtlas, but is not limited to these sources. It can be extended to consider additional data repositories and the user's own peptide libraries.
University of Victoria — Genome British Columbia Proteomics Centre, University of Victoria, Victoria, BC, Canada; Center for Proteomics and Metabolomics, Leiden University Medical Center, Netherlands; Mass Spectrometry Laboratory, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, Warsaw, Poland; Department of Biochemistry & Microbiology, University of Victoria, Victoria, BC, Canada
PeptidePicker funding source(s)
This work was supported by the Genome Canada and Genome British Columbia, the UVic-Genome British Columbia Proteomics Centre and the Dutch Organization for Scientific Research (Nederlandse Organisatie voor Wetenschappelijk Onderzoek, NWO) grants Q16 NRG-2010.06 and VI-917.11.398.