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Information


Unique identifier OMICS_21348
Name Peptidome
Restrictions to use None
Community driven No
Data access File download
User data submission Allowed
Maintained No

Additional information


ftp://ftp.ncbi.nih.gov/pub/peptidome/

Publication for Peptidome

Peptidome citations

 (47)
library_books

Assessment by Matrix‐Assisted Laser Desorption/Ionization Time‐of‐Flight Mass Spectrometry of the Effects of Preanalytical Variables on Serum Peptidome Profiles Following Long‐Term Sample Storage

2018
Proteomics Clin Appl
PMCID: 5947747
PMID: 29349874
DOI: 10.1002/prca.201700047

[…] ing how low‐molecular‐weight peptides in serum are affected by long‐term storage. Therefore, in the present study, we tested the effects of long‐term storage for up to 12 months on serum proteome and peptidome profiles. Furthermore, to date there have been no detailed investigations into how the proteome and peptidome patterns of serum samples stored at −20 °C differ from those stored at −80 °C. I […]

library_books

CD74 regulates complexity of tumor cell HLA class II peptidome in brain metastasis and is a positive prognostic marker for patient survival

2018
PMCID: 5831742
PMID: 29490700
DOI: 10.1186/s40478-018-0521-5

[…] []. We independently transfected nine replicates each of control and siRNA knockdown condition (nine T175 flasks each). Due to the large amounts of cells which are necessary for sufficiently deep HLA peptidome analysis, we pooled all cells for each condition. Mass spectrometry was performed in 5 technical replicates for each condition to allow for statistical evaluation of label-free quantitation […]

library_books

Quantitative peptidomics of endogenous peptides involved in TGF β1 induced epithelial mesenchymal transition of renal epithelial cells

2018
PMCID: 5841401
PMID: 29531806
DOI: 10.1038/s41420-017-0001-x

[…] Annotation of proteolytic cleavage and other relevant information of the identified peptides were acquired using various peptidase/peptidome databases, including MEROPS (http://merops.sanger.ac.uk), TopFINDer (http://clipserve.clip.ubc.ca/topfind/topfinder), DegraBase (https://wellslab.ucsf.edu/degrabase), and SProtP (http://repr […]

library_books

High throughput and Sensitive Immunopeptidomics Platform Reveals Profound Interferonγ Mediated Remodeling of the Human Leukocyte Antigen (HLA) Ligandome*

2017
PMCID: 5836376
PMID: 29242379
DOI: 10.1074/mcp.TIR117.000383

[…] mented surface presentation of HLA complexes could lead to a higher probability of presentation and, hence, recognition of immunogenic epitopes. However, no high-quality mapping of the IFNγ modulated peptidome has been reported so far and therefore, the overall properties of the presented repertoire on stimulation remain unknown.Here, we uncovered a global modulation in the immunopeptidome on expo […]

library_books

An Analysis of Natural T Cell Responses to Predicted Tumor Neoepitopes

2017
Front Immunol
PMCID: 5694748
PMID: 29187854
DOI: 10.3389/fimmu.2017.01566

[…] l peptides were missing or partially missing. For the missing normal peptides, we used “pepmatch,” a program available as part of MuPeXI (), to identify the most similar peptide from the normal human peptidome. The normal human peptidome was defined as all unique peptides of lengths 8–11 extracted from human proteins available in Ensembl release 85, based on human genome GRCh38. Out of 820 neopept […]

library_books

‘Hotspots’ of Antigen Presentation Revealed by Human Leukocyte Antigen Ligandomics for Neoantigen Prioritization

2017
Front Immunol
PMCID: 5654951
PMID: 29104575
DOI: 10.3389/fimmu.2017.01367

[…] MS-based immunopeptidomics is a powerful approach to shed light on the selective sampling of the proteome. Because it captures the actual presented peptidome, it may bypass the need to computationally predict ligands. Therefore, it is also a promising method to directly identify presented neoantigens. However, enough tumor tissue is available onl […]

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Peptidome institution(s)
National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA

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