Percentile-normalization method statistics

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Percentile-normalization method specifications


Unique identifier OMICS_29202
Name Percentile-normalization method
Software type Application/Script
Interface Command line interface
Restrictions to use None
Input data The OTU table (samples as rows and OTUs/phylotypes as columns), the list of case sample names in the OTU table and the list of control sample names in the OTU table.
Operating system Unix/Linux
Programming languages Python
Computer skills Advanced
Stability Stable
Maintained Yes



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  • person_outline Eric Alm <>

Publication for Percentile-normalization method

Percentile-normalization method in publications

PMCID: 4161293
PMID: 25211773
DOI: 10.1371/journal.pcbi.1003831

[…] high sequence identity (>95%) and short sequence length (<60%) to the query sequence were eradicated, with the resulting homologous sequences to calculate amino acid conservation scores. the percentile normalization method to normalize the conservation scores, as done by yang et al. , was performed to compare the conserved degree of substrate, allosteric, and surface sites., molecular […]

PMCID: 3395594
PMID: 22807670
DOI: 10.1371/journal.pcbi.1002612

[…] (36.9±12.6, ). conservation scores of residues were calculated from the resulting homologous sequence set using the rate4site algorithm . we normalized the conservation scores by using the percentile normalization method to compare conservation scores of different enzymes. using the same strategy, we collected homologous sequences of e. coli fbpase to calculate conservation scores. […]

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Percentile-normalization method institution(s)
Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA; Center for Microbiome Informatics and Therapeutics, Cambridge, MA, USA; The Broad Institute of MIT and Harvard, Cambridge, MA, USA
Percentile-normalization method funding source(s)
Supported by the Rasmussen Family Foundation through the Center for Microbiome Informatics and Therapeutics.

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