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Pharmacogenomic tools

Pharmacogenetics, one of the cornerstones of personalized medicine, has the potential to change the way in which health care is offered by stratifying patients into various pretreatment categories, such as likely responders, likely non-responders or…
DrugBank
Dataset

DrugBank

A comprehensive online database containing extensive biochemical and…

A comprehensive online database containing extensive biochemical and pharmacological information about drugs, their mechanisms and their targets. Since it was first described in 2006, DrugBank has…

CPIC
Dataset

CPIC Clinical Pharmacogenetics Implementation Consortium

Consists of Pharmacogenomics Research Network members, PharmGKB staff, and…

Consists of Pharmacogenomics Research Network members, PharmGKB staff, and experts in pharmacogenetics, pharmacogenomics, and laboratory medicine. The CPIC provides a database of guidelines, a list…

HIBAG
Desktop

HIBAG HLA Genotype Imputation with Attribute Bagging

Imputes HLA types using single-nucleotide polymorphism (SNP) data. HIBAG is a…

Imputes HLA types using single-nucleotide polymorphism (SNP) data. HIBAG is a software package which combines the concepts of attribute bagging, an ensemble classifier method, with haplotype…

PASS
Desktop

PASS Prediction of Activity Spectra for Substances

Predicts many kinds of biological activity for compounds from different…

Predicts many kinds of biological activity for compounds from different chemical series based on their 2D structural formulas. PASS finds new targets mechanisms for some ligands. It can reveal new…

SNP2HLA
Desktop

SNP2HLA

Allows a facile amino-acid focused downstream analysis. SNP2HLA is a software…

Allows a facile amino-acid focused downstream analysis. SNP2HLA is a software which imputes amino acid polymorphisms and single nucleotide polymorphisms (SNPs) in human leukocyte antigenes (HLA)…

PharmGKB
Dataset

PharmGKB

A comprehensive resource that curates knowledge about the impact of genetic…

A comprehensive resource that curates knowledge about the impact of genetic variation on drug response for clinicians and researchers. PharmGKB has refocused on curating knowledge rather than housing…

SPHINX
Dataset

SPHINX Sequence and Phenotype Integration Exchange

Contains a secure, de-identified, web-accessible repository of genomic…

Contains a secure, de-identified, web-accessible repository of genomic variants. SPHINX is a resource for eMERGE-PGx. Sequence variants determined from PGRNseq on all enrolled eMERGE-PGx participants…

rcellminer
Desktop

rcellminer

Provides a wide range of functionality to help R users access and explore…

Provides a wide range of functionality to help R users access and explore molecular profiling and drug response data for the NCI-60. The package enables flexible programmatic access to…

GTR
Dataset

GTR Genetic Testing Registry

Provides a central location for voluntary submission of genetic test…

Provides a central location for voluntary submission of genetic test information by providers.

Pharmacogenetic…
Dataset

Pharmacogenetics of Membrane Transporters

Provides the target for many commonly used prescription drugs and is a major…

Provides the target for many commonly used prescription drugs and is a major determinant of the absorption, distribution and elimination of many clinically used drugs. The Pharmacogenetics of…

CellMiner
Dataset

CellMiner

A relational database tool for storing, querying, integrating, and downloading…

A relational database tool for storing, querying, integrating, and downloading molecular profile data on the NCI-60 and other cancer cell types. The newest CellMiner version includes integration of…

OmicKriging
Desktop

OmicKriging

Predicts complex traits. OmicKriging leverages and integrates similarity in…

Predicts complex traits. OmicKriging leverages and integrates similarity in genetic, transcriptomic, and/or other large scale omics data. It emphasizes the use of a wide variety of systems-level…

PharmacoGx
Desktop

PharmacoGx

An R package enabling users to download and interrogate large pharmacogenomic…

An R package enabling users to download and interrogate large pharmacogenomic datasets that were extensively curated to ensure maximum overlap and consistency. PharmacoGx provides parallelized…

FDALabel
Dataset

FDALabel

Offers access to drug-labeling data and facilitates their use in regulatory…

Offers access to drug-labeling data and facilitates their use in regulatory science, drug development, scientific research, and clinical application. FDALabel contains over 95 000 full-text…

FINDbase
Dataset

FINDbase

An online resource documenting frequencies of pathogenic genetic variations…

An online resource documenting frequencies of pathogenic genetic variations leading to inherited disorders in various populations worldwide.

VP
Desktop

VP Virtual Pharmacist

A web tool that interprets personal genome for the impact of genetic variation…

A web tool that interprets personal genome for the impact of genetic variation on drug response. Virtual Pharmacist can take variants data (VCF format), microarray SNP genotyping data and…

ePGA
Dataset

ePGA electronic Pharmacogenomics Assistant

Offers personalized recommendations based on pharmacogenomics evidence. ePGA is…

Offers personalized recommendations based on pharmacogenomics evidence. ePGA is a web-based application that combines: (i) information retrieval on state of the art PGx variants, genes, drugs, and…

DruGeVar
Dataset

DruGeVar

Triangulates drugs with genes and pharmacogenomic biomarkers. The DruGeVar…

Triangulates drugs with genes and pharmacogenomic biomarkers. The DruGeVar database enables the user to draw such useful conclusions from a large dataset not only by visualizing, sorting and…

WarfarinDosing
Dataset

WarfarinDosing

A free Web site to help doctors and other clinicians begin warfarin therapy by…

A free Web site to help doctors and other clinicians begin warfarin therapy by estimating the therapeutic dose in patients new to warfarin.

PharmCAT
Desktop

PharmCAT Pharmacogenomic Clinical Annotation Tool

Extracts all Clinical Pharmacogenetics Implementation Consortium (CPIC)…

Extracts all Clinical Pharmacogenetics Implementation Consortium (CPIC) guideline gene variants from a genetic dataset, interprets the variant alleles, and generates a report. The CPIC pipeline…

HGDP-CEPH
Dataset
Pharmacogenomic…
Dataset

Pharmacogenomic Biomarkers in Drug Labeling

Lists food and drug administration (FDA)-approved drugs with pharmacogenomic…

Lists food and drug administration (FDA)-approved drugs with pharmacogenomic information in their labeling. Pharmacogenomic Biomarkers in Drug Labeling provides a table of the drugs that includes…

PGMD
Dataset

PGMD PharmacoGenomic Mutation Database

A resource for identifying all published genetic variants that have been shown…

A resource for identifying all published genetic variants that have been shown to affect drug response in patients.

PACdb
Dataset

PACdb Pharmacogenomics And Cell database

A central repository of pharmacology-related phenotypes that integrates…

A central repository of pharmacology-related phenotypes that integrates genotypic, gene expression and pharmacological data obtained via lymphoblastoid cell lines.

CellMiner…
Web
Desktop

CellMiner Companion

A web application that enables researchers to explore the output of CellMiner…

A web application that enables researchers to explore the output of CellMiner queries. The data from multiple files is summarized, assembled into a single data matrix, z-score normalized, clustered,…

CancerGEM KB
Dataset

CancerGEM KB Cancer Genomic Evidence-based Medicine Knowledge Base

A continuously updated searchable online resource that provides access to…

A continuously updated searchable online resource that provides access to scientific information on the use of genomic information in cancer care and prevention.

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