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- person_outline Andrew Massey
Publication for PhenoLOGIC
Imaging Based Screen Identifies Laminin 411 as a Physiologically Relevant Niche Factor with Importance for i Hep Applications
[…] Data were analyzed with GraphPad Prism for Pearson Correlation Analyses and t tests. t Tests were plotted as mean ± SD or mean ± SEM where specified. Phenologic and Spotfire (PerkinElmer) were also used for multivariate analysis (Random Forrest), PCA plot, and SOM algorithm. […]
Inhibition of Chk1 with the small molecule inhibitor V158411 induces DNA damage and cell death in an unperturbed S phase
[…] ng modalities on the Operetta high content imaging system at 10x magnification. Cell confluency was determined from the brightfield images using the ‘Find Texture Regions’ building block coupled with PhenoLOGIC texture-based segmentation in the Harmony software. Cell number was determined by analysis of the digital phase images with the ‘Find Cells’ building block in Harmony. […]
Tumour growth environment modulates Chk1 signalling pathways and Chk1 inhibitor sensitivity
[…] mperature was maintained at 37 °C and CO2 at 5% with the live cell chamber module.Cell confluency was determined from the brightfield images using the Find Texture Regions building block coupled with PhenoLOGIC texture based segmentation in the Harmony software. Cell number was determined by analysis of the digital phase images with the Find Cells building block in Harmony. […]
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