PHENOstruct specifications


Unique identifier OMICS_13456
Name PHENOstruct
Software type Package/Module
Interface Command line interface
Restrictions to use None
Input data PHENOstruct takes the set of feature vectors and HPO annotations associated with each gene as input for training.
Operating system Unix/Linux
Computer skills Advanced
Version 0.1
Stability Stable
Maintained Yes




No version available


  • person_outline Asa Ben-Hur

Publication for PHENOstruct

PHENOstruct citation


Prediction of Human Phenotype Ontology terms by means of hierarchical ensemble methods

BMC Bioinformatics
PMCID: 5639780
PMID: 29025394
DOI: 10.1186/s12859-017-1854-y

[…] We compared the hierarchical ensemble methods for DAGs (HTD, “” subsection) and TPR and its variants, (“” subsection) against several state-of-the-art and baseline methods: PHENOstruct, a state-of-the art joint-kernel structured support vector machine approach []. This method uses the product of the input and output space kernel to construct the joint kernel. The rationa […]

PHENOstruct institution(s)
Department of Computer Science, Colorado State University, Fort Collins, CO, USA; Computational Bioscience Program, University of Colorado School of Medicine, Aurora, CO, USA; Department of Computing and Information Systems, University of Melbourne, Parkville, VIC, Australia; Health and Biomedical Informatics Centre, University of Melbourne, Parkville, VIC, Australia
PHENOstruct funding source(s)
This work was supported by the NSF Advances in Biological Informatics program through grants number 0965768 and 0965616.

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