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PhosphoNET specifications

Information


Unique identifier OMICS_05985
Name PhosphoNET
Restrictions to use None
Maintained Yes

Taxon


  • Primates
    • Homo sapiens

Publication for PhosphoNET

PhosphoNET citations

 (9)
library_books

Kinome and phosphoproteome of high grade meningiomas reveal AKAP12 as a central regulator of aggressiveness and its possible role in progression

2018
Sci Rep
PMCID: 5794791
PMID: 29391485
DOI: 10.1038/s41598-018-19308-y

[…] The GO and PCA analyses were performed by PANTHER 10.0. Kinase analysis by GPS 2.1 and PhosphoNet Kinexus. Kinome trees were annotated using Kinome Render. IPA (Ingenuity Systems, Redwood City, CA) was used to identify mechanisms, functions, pathways, and predict upstream regulators. Gr […]

library_books

Identification of a novel cAMP dependent protein kinase A phosphorylation site on the human cardiac calcium channel

2017
Sci Rep
PMCID: 5680263
PMID: 29123182
DOI: 10.1038/s41598-017-15087-0

[…] To predict the most probable site for protein kinase A phosphorylation, a comparative study of available phosphorylation databases (Kinexus PhosphoNET, PhosphoSitePlus, PHOSIDA) and trials of in silico phosphorylation site prediction programs (NetPhosK 1.0, NetworKin, pkaPS, GPS 2.1, PPSP, Scansite,) were used to predict the most likely P […]

library_books

The prohibitin repressive interaction with E2F1 is rapidly inhibited by androgen signalling in prostate cancer cells

2017
Oncogenesis
PMCID: 5523065
PMID: 28504694
DOI: 10.1038/oncsis.2017.32

[…] exported out of the nucleus, thus allowing androgen-mediated cell cycle entry.Analysis of the potential phosphorylation sites, listed above, via KinasePhos2.0 (http://kinasephos2.mbc.nctu.edu.tw) and Phosphonet (http://www.phosphonet.ca) implicated GRK (G-protein coupled receptor kinase) and Akt/PKB (protein kinase B) to be the most likely kinase that would target PHB for phosphorylation, but no e […]

library_books

The Dyslexia susceptibility Protein KIAA0319 Inhibits Axon Growth Through Smad2 Signaling

2017
PMCID: 5905272
PMID: 28334068
DOI: 10.1093/cercor/bhx023

[…] ning the TM and cytosolic domains) was performed using Clustal Omega (http://www.ebi.ac.uk/Tools/msa/clustalo/). Putative phosphorylation sites within the KIAA0319 cytosolic tail were predicted using PhosphoNet (http://www.phosphonet.ca, Kinexus Bioinformatics Corporation). Single missense mutants of predicted phosphorylation sites between positions 984 and 1023, corresponding to the juxtamembrane […]

library_books

Reciprocal regulation of ARPP 16 by PKA and MAST3 kinases provides a cAMP regulated switch in protein phosphatase 2A inhibition

2017
eLife
PMCID: 5515580
PMID: 28613156
DOI: 10.7554/eLife.24998.035

[…] samples, while an additional 7 phospho-sites were found only in the samples incubated with forskolin. Notably, inspection of the amino acid sequence of MAST3 using bioinformatics tools KinasePhos (), PhosphoNet (), NetPhos 3.1 () also identified Thr389 (RHRDT[389]RQR) as a potential PKA site. Although MS/MS analysis of a chymotryptic digest of MAST3-HA showed the presence of a phospho-peptide cont […]

library_books

Mammalian FMRP S499 Is Phosphorylated by CK2 and Promotes Secondary Phosphorylation of FMRP

2016
eNeuro
PMCID: 5116651
PMID: 27957526
DOI: 10.1523/ENEURO.0092-16.2016

[…] harmacological subgroups, we switched to a candidate kinase approach. Candidate kinases capable of phosphorylating FMRP S499 were initially identified using two in silico kinase prediction platforms, phosphonet.ca and iGPS. From this list, we chose to test the top-ranked kinases available in the Kinexus recombinant kinase library (). Added to this candidate group were kinases known to be involved […]

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PhosphoNET institution(s)
Department of Computer Science, University of British Columbia, Vancouver, Canada

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