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PhosphoNetworks specifications

Information


Unique identifier OMICS_11526
Name PhosphoNetworks
Restrictions to use Academic or non-commercial use
Community driven No
Data access File download, Browse
User data submission Not allowed
Maintained Yes

Maintainer


  • person_outline Jiang Qian

Publication for PhosphoNetworks

PhosphoNetworks citations

 (3)
library_books

Integrating Phosphoproteomics and Bioinformatics to Study Brassinosteroid Regulated Phosphorylation Dynamics in Arabidopsis

2015
BMC Genomics
PMCID: 4506601
PMID: 26187819
DOI: 10.1186/s12864-015-1753-4

[…] ciated with specific kinases by searching manually the literature and databases, including PhosPhAt (the Arabidopsis phosphorylation site database) [], HPRD (Human Protein Reference Database) [], and PhosphoNetworks []. A motif-kinase association was constructed if the motif was identical to the recognizing pattern of a given kinase reported by literature or described in a database.To reveal the d […]

library_books

Differential Reprogramming of Isogenic Colorectal Cancer Cells by Distinct Activating KRAS Mutations

2015
J Proteome Res
PMCID: 4356034
PMID: 25599653
DOI: 10.1021/pr501191a

[…] 5 and cluster 6 members, indicating coordinated increase or decrease of phosphorylation at multiple sites within a protein.Given the central role of kinases in mediating Ras responses and modulating phosphonetworks, we examined their contribution to our data sets. In total, we detected peptides from 38 kinases ( Table 3). A total of 35 kinase phosphopeptides out of 96 were responsive (≥1.5-fold c […]

library_books

Integrating phosphoproteomics in systems biology

2014
Comput Struct Biotechnol J
PMCID: 4204398
PMID: 25349677
DOI: 10.1016/j.csbj.2014.07.003

[…] ks. High-throughput technologies and computational approaches have been developed to identify these relevant kinase–substrate relationships, and the results are deposited into network databases, like phosphoNetworks and phosphoPOINT . PhosphoNetworks contains high-resolution phosphorylation networks derived from protein microarray and MS-based experiments, and it integrates a range of approaches t […]

Citations

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PhosphoNetworks institution(s)
Department of Ophthalmology, Johns Hopkins School of Medicine, Johns Hopkins School of Medicine, Baltimore, MD, USA; Department of Pharmacology and Molecular Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA; Center for High-Throughput Biology, Johns Hopkins School of Medicine, Baltimore, MD, USA; Department of Biology, North Carolina Agricultural and Technical State University, Greensboro, NC, USA; The Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins School of Medicine, Baltimore, MD, USA
PhosphoNetworks funding source(s)
NIH grants (R01 DK073368, DP1 CA174423, RR020839, DK082840, GM076102, CA125807, CA160036, HG006434 and RR020839) (in part)

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