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Kinase-substrate network databases | Protein interaction data analysis

Kinase-substrate network databases | Protein interaction data analysis

Protein phosphorylation catalyzed by kinases plays crucial regulatory roles in intracellular signal transduction. With the increasing number of experimental phosphorylation sites that has been identified by mass spectrometry-based proteomics, the desire to explore the networks of protein kinases and substrates is motivated.

Source text:
(Lee et al., 2011) RegPhos: a system to explore the protein kinase-substrate phosphorylation network in humans. Nucleic Acids Res.

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