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PhyloPat specifications


Unique identifier OMICS_08064
Name PhyloPat
Restrictions to use None
Maintained No


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Publications for PhyloPat

PhyloPat citations


ProteinHistorian: Tools for the Comparative Analysis of Eukaryote Protein Origin

PLoS Comput Biol
PMCID: 3386163
PMID: 22761559
DOI: 10.1371/journal.pcbi.1002567

[…] r protein age enrichment analysis and visualization. However, there are other web servers that perform complementary phylogenetic analyses based on existing protein family databases. For example, the PhyloPat server performs regular expression searches on phylogenetic profiles. Similarly, PhyloPro allows a user to visualize the evolutionary trajectory of a set of proteins, such as a metabolic pa […]


Similarly Strong Purifying Selection Acts on Human Disease Genes of All Evolutionary Ages

Genome Biol Evol
PMCID: 2817408
PMID: 20333184
DOI: 10.1093/gbe/evp013

[…] tained the youngest genes and the age group 9 contained the oldest genes. The age was estimated using Dollo parsimony (; ) by finding the most highly divergent lineage in which an ortholog (using the Phylopat pipeline; , ) or a homolog (using BlastP) of a particular human gene could be found (see Materials and Methods for details).Two binning approaches, equally populated bins and equally spaced b […]

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PhyloPat institution(s)
Computational Drug Discovery (CDD), CMBI, NCMLS, Radboud University Nijmegen Medical Centre, Nijmegen, Netherlands; Department of Molecular Design and Informatics, Schering-Plough, Netherlands
PhyloPat funding source(s)
This work was part of BioRange SP3.2.2 project of the Netherlands Bioinformatics Centre (NBIC), and was supported financially by Schering-Plough corporation.

PhyloPat review

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Anonymous user #1085

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Very useful tool!