PiNAT specifications


Unique identifier OMICS_20062
Name PiNAT
Alternative name Protein interaction Network Assessment Tool
Software type Application/Script
Interface Command line interface
Restrictions to use None
Input data A list of protein names (UniProt, Swissprot / Trebml, Genbank or DIP) or your own network.
Output data A visual description of the predicted spatial flow of a pathway in the cell and a list of scores for each interaction, based on different sequence-level analyses of the individual proteins.
Operating system Unix/Linux
Computer skills Advanced
Stability Stable
Maintained Yes


No version available


  • person_outline Pinat Team

Publication for Protein interaction Network Assessment Tool

PiNAT citations


Solution Structural Analysis of the Single Domain Parvulin TbPin1

PLoS One
PMCID: 3416822
PMID: 22900083
DOI: 10.1371/journal.pone.0043017

[…] ivalent to His59, Lys63, Cys113, Leu122, Met130, Phe134, Ser154 and His157 in hPin1) did not experience significant chemical shift perturbations . Similarly, His12, Lys16, Cys70, Leu79, and His114 in PinAt (equivalent to His9, Lys13, Cys65, Leu74 and His109 in TbPin1) also showed non-significant chemical shift perturbations in 2D 1H-15N HSQC spectrum . However, in 2D 1H-13C HSQC spectrum, the two […]


Computational Study of pH sensitive Hydrogel based Microfluidic Flow Controllers

PMCID: 4030935
PMID: 24956303
DOI: 10.3390/jfb2030195

[…] The boundary conditions can be summarized as follows: At the inlet of the channel, we prescribe (24)ck=ck,in,ψ=ψin,p=pinAt the outlet of the channel, we prescribe (25)∇ck⋅n=∇ψ⋅n=0,p=poutAt the walls of the channel, we prescribe (26)∇ck⋅n=∇ψ⋅n=0,v(f)=0In the centre of hydrogel, we prescribe (27)u=0At the hydrogels/fl […]

PiNAT institution(s)
Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA; Columbia University Center for Computational Biology and Bioinformatics (C2B2), New York, NY, USA; NorthEast Structural Genomics Consortium (NESG), Columbia University, New York, NY, USA; Department of Biomedical Informatics, Columbia University, New York, NY, USA
PiNAT funding source(s)
Supported by the grants: RO1-GM64633-01 from the National Institutes of Health (NIH) and the grant RO1-LM07329-01 from the National Library of Medicine (NLM).

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