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Enables users to access information on all these aspects for studying microbial proteomes. PBIT is an online webserver that has been developed for screening of microbial proteomes for critical features of human drug targets such as being non-homologous to human proteome as well as the human gut microbiota, essential for the pathogen’s survival, participation in pathogen-specific pathways etc. The tool has been validated by analyzing 57 putative targets of Candida albicans documented in literature. PBIT integrates various in silico approaches known for drug target identification and will facilitate high throughput prediction of drug targets for infectious diseases, including multi-pathogenic infections.

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PBIT classification

PBIT specifications

Software type:
Package
Restrictions to use:
None
Input format:
FASTA
Stability:
Stable
Interface:
Web user interface
Input data:
A file containing protein sequence
Computer skills:
Basic

PBIT support

Documentation

Credits

Publications

Institution(s)

ICMR Biomedical Informatics Center, National Institute for Research in Reproductive Health, Mumbai, India

Funding source(s)

This work [RA/389/06-2016] was supported by grants from Department of Science and Technology, India and Indian Council of Medical Research.

Link to literature

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