Piphillin specifications


Unique identifier OMICS_19013
Name Piphillin
Interface Web user interface
Restrictions to use None
Input data An OTU abundance table and a representative sequence.
Input format CSV, FASTA
Computer skills Basic
Stability Stable
Maintained Yes


  • person_outline Todd DeSantis

Publication for Piphillin

Piphillin citations


Amphibian chytridiomycosis outbreak dynamics are linked with host skin bacterial community structure

Nat Commun
PMCID: 5814395
PMID: 29449565
DOI: 10.1038/s41467-018-02967-w

[…] the function heatmap.2 in the gplots package in R.To examine whether function of bacterial communities from enzootic and epizootic metamorph populations differed, gene prediction was performed using Piphillin. A sequence identity cut-off of 97% was used and sequences were assigned putative function using the KEGG reference database (May 2017 release). Beta diversity of KEGG orthology (KO) abundan […]


Gut Dysbiosis and Muscle Aging: Searching for Novel Targets against Sarcopenia

PMCID: 5893006
PMID: 29686533
DOI: 10.1155/2018/7026198

[…] ontent even in sequenced genomes not available by using ancestral state reconstruction algorithms. Other examples are Tax4Fun [], which relies on the KEGG database, the SILVA SSU Ref NR database, and Piphillin [], which has implemented an inference tool that works with any current genome database and has improved correlation and accuracy for clinical samples compared with PICRUSt and Tax4Fun [].Me […]

Piphillin institution(s)
Informatics Department, Second Genome Inc., South San Francisco, CA, USA; Bluestone Center for Clinical Research and the Department of Oral and Maxillofacial Surgery, New York University College of Dentistry, New York, NY, USA; Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA; Research and External Scientific Innovation Department, Allergan PLC, Irvine, CA, USA
Piphillin funding source(s)
Supported in part by the National Center for Research Resources, the National Center for Advancing Translational Sciences, and the Office of the Director, National Institutes of Health, through University of San Francisco CTSI grant number UL1 RR024129, and individual investigator awards from the National Cancer Institute grant (R01 CA131286, R21 CA163019) and the National Institute of Dental and Craniofacial Research (R01 DE019796); and in part by Second Genome Inc and Allergan PLC.

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