PISCES statistics

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Citations per year

Number of citations per year for the bioinformatics software tool PISCES

Tool usage distribution map

This map represents all the scientific publications referring to PISCES per scientific context
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Associated diseases

This word cloud represents PISCES usage per disease context

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PISCES specifications


Unique identifier OMICS_05153
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Publication for PISCES

PISCES citations


Minimizing proteome redundancy in the UniProt Knowledgebase

PMCID: 5199198
PMID: 28025334
DOI: 10.1093/database/baw139

[…] of our Reference proteomes.There are a host of software programs and methods aimed at minimizing redundancy within protein sequence databases. These include SkipRedundant (), Decrease Redundancy (), Pisces (), UniqueProt (), CD-HIT (), FSA-BLAST (), BlastClust (ftp://ftp.ncbi.nih.gov/blast/documents/blastclust.html), MinSet (), BlastCuller (), FastCluster (), Leaf (), UCLUST () and Compressive ge […]


Implication of Terminal Residues at Protein Protein and Protein DNA Interfaces

PLoS One
PMCID: 5017611
PMID: 27611671
DOI: 10.1371/journal.pone.0162143
call_split See protocol

[…] (dimers) and those extracted from higher order complexes (K-mers), from information available in the PDB.We filtered the DIMER70 list in order to reduce the redundancy between monomers to 25%, using PISCES (http://dunbrack.fccc.edu/PISCES.php) [] with the following input parameters: sequence percentage identity <25%, resolution <3Å, R-factor <0.3, sequence length between 40 and 10,000, include no […]


A novel secondary structure based on fused five membered rings motif

Sci Rep
PMCID: 4980606
PMID: 27511362
DOI: 10.1038/srep31483

[…] A non-redundant dataset of 4114 protein chains present in 3976 PDB (Protein Data Bank), files were selected using PISCES server, such that the resolution ≤2 Å, R-factor is ≤0.2, and the sequence identity between any two protein sequences is ≤25%. The files used are given in. REDUCE was used to fix the hydrogen po […]


Ab Initio Coordination Chemistry for Nickel Chelation Motifs

PLoS One
PMCID: 4435748
PMID: 25985439
DOI: 10.1371/journal.pone.0126787
call_split See protocol

[…] uctures were considered and all NMR and theoretical models were excluded. The initial dataset comprised about 928 crystal structures. The dataset was further was culled at 40% sequence identity using PISCES server [] to remove redundant structures due to homodimers and identical entries. Other threshold parameters employed included resolution between 0.0–3.0Å and R value of 0.3. The resulting cull […]


Briefing in Application of Machine Learning Methods in Ion Channel Prediction

Sci World J
PMCID: 4415473
PMID: 25961077
DOI: 10.1155/2015/945927

[…] y, because the high similarity data will lead to overestimating the performance of the proposed predictors.In order to exclude highly similar sequences from these datasets, BLASTClust, CD-HIT [], and PISCES [] have been developed and could be freely obtained at the addresses listed in . BLASTClust is a program that can be used to cluster either protein or nucleotide sequences. However, since it re […]


An Overview of the Prediction of Protein DNA Binding Sites

Int J Mol Sci
PMCID: 4394471
PMID: 25756377
DOI: 10.3390/ijms16035194

[…] subsequences of other proteins in a data set were eliminated. The frequently used clustering program contains blastclust (available from the National Center for Biotechnology Information, NCBI), the PISCES Web server [], and the H-CD-HIT program []. Using the metaDBSite method, the protein–DNA complexes with a resolution better than 3.0 Å were submitted to H-CD-HIT to obtain a nonredundant data s […]

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PISCES institution(s)
Institute for Cancer Research, Fox Chase Cancer Center, Philadelphia, PA, USA

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