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PLSNET specifications


Unique identifier OMICS_14585
Software type Package/Module
Interface Command line interface
Restrictions to use None
Input data Gene expression measurements for p genes in experimental conditions.
Operating system Unix/Linux
Programming languages MATLAB
Computer skills Advanced
Stability Stable
Maintained Yes




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  • person_outline Donghui Guo

Publication for PLSNET

PLSNET citation


Identifying Network Perturbation in Cancer

PLoS Comput Biol
PMCID: 4856318
PMID: 27145341
DOI: 10.1371/journal.pcbi.1004888

[…] t-test p-values [, , ]. 3) Learning a condition-specific conditional dependency network for each condition and comparing the networks between conditions: Gill et al. (2010) proposed a method, called PLSNet, that fits a partial least squares model to each gene, computes a connectivity scores between genes, and then calculates the L1 distance between score vectors to estimate network perturbation [ […]

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PLSNET institution(s)
Department of Electronic Engineering, Xiamen University, Fujian, China; Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China; School of Mathematics and Computer Science, Fujian Normal University, Fujian, China
PLSNET funding source(s)
This research was supported by Research Fund for National Natural Science Foundation of China (General Program) under Grant No. 61274133 and Shenzhen Technology Development Foundation Grant No. CXZZ20150813155917544.

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