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Protocols

PMAP specifications

Information


Unique identifier OMICS_02766
Name PMAP
Alternative name Proteolysis MAP
Restrictions to use None
Maintained No

Publication for Proteolysis MAP

PMAP citations

 (10)
library_books

Cupincin: A Unique Protease Purified from Rice (Oryza sativa L.) Bran Is a New Member of the Cupin Superfamily

2016
PLoS One
PMCID: 4827828
PMID: 27064905
DOI: 10.1371/journal.pone.0152819

[…] rehensive data base of proteases and inhibitors and Protident [(http://www.csbio.sjtu.edu.cn/bioinf/Protease/), ()] showed negative results, however submission of modelled 3D structure of cupincin to PMAP database [] (http://www.proteolysis.org) which combines five databases (ProteaseDB, SubstrateDB, CutDB, ProfileDB and PathwayDB) and a computational toolkit to create an integrated reasoning envi […]

library_books

A formin nucleated actin aster concentrates cell wall hydrolases for cell fusion in fission yeast

2015
PMCID: 4384723
PMID: 25825517
DOI: 10.1083/jcb.201411124

[…] 2 signal () was measured by following the x and y coordinates of the highest intensity pixel of the Myo52-tdTomato signal in each mating partner over time. The homothallic strain used, also expressed pmap3:GFP as a marker for the mating type. Time interval of the video is 7.2 min. During the Myo52 crescent phase, we recorded the coordinates of the maximum fluorescence intensity. Displacement was t […]

library_books

The C Terminal Fragment of Prostate Specific Antigen, a 2331 Da Peptide, as a New Urinary Pathognomonic Biomarker Candidate for Diagnosing Prostate Cancer

2014
PLoS One
PMCID: 4169392
PMID: 25233230
DOI: 10.1371/journal.pone.0107234

[…] or to the serum PSA. These results suggest that the biomarker concentration in the urine sample might be more useful than that of serum PSA for diagnosing PCa.We performed a sequence search using the PMAP-CutDB proteolytic event database (URL: http://cutdb.burnham.org/) in order to detect candidate proteases that cleave specific amino acid sequences in PSA. CutDB is one of the PMAP web sites whose […]

library_books

New Milk Protein Derived Peptides with Potential Antimicrobial Activity: An Approach Based on Bioinformatic Studies

2014
Int J Mol Sci
PMCID: 4159866
PMID: 25141106
DOI: 10.3390/ijms150814531

[…] of multivariate statistical methods to determine potentially antimicrobial motifs released from the analyzed proteins. In silico proteolysis can be performed with the use of several programs, such as PMAP (www.proteolysis.org/proteases) [] and PeptideCutter (www.expasy.org/tools/peptidecutter/) [], or a dedicated tool in the BIOPEP database. Detailed description of BIOPEP database has been present […]

library_books

Design of Embedded Hybrid Antimicrobial Peptides with Enhanced Cell Selectivity and Anti Biofilm Activity

2014
PLoS One
PMCID: 4063695
PMID: 24945359
DOI: 10.1371/journal.pone.0098935

[…] First, RI16 was obtained through being truncated from α-helical peptide PMAP-36(1–20), which is a 16-residue perfectly amphipathic parental peptide. Secondly, an anti-biofilm sequence FV7 was embedded in the peptide RI16 to substitute RR7 (RKKT RKR). Aimed sequence RR7 lo […]

call_split

Antimicrobial Properties and Membrane Active Mechanism of a Potential α Helical Antimicrobial Derived from Cathelicidin PMAP 36

2014
PLoS One
PMCID: 3897731
PMID: 24466055
DOI: 10.1371/journal.pone.0086364
call_split See protocol

[…] According to the three-dimensional structure and helical wheel projection, we designed a series of derivatives by truncating and residue substituting of PMAP-36 (). Firstly, different peptide fragments derived from PMAP-36 sequence was obtained. The 24-residue peptide, GI24 contained the entire α-helical region and all of the cationic amino acids of P […]


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PMAP institution(s)
The Center on Proteolytic Pathways, The Cancer Research Center and The Inflammatory and Infectious Disease Center, The Burnham Institute for Medical Research, La Jolla, CA, USA

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