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PMes specifications


Unique identifier OMICS_18511
Name PMes
Interface Web user interface
Restrictions to use None
Input data One or multiple human or other species protein sequences.
Input format FASTA
Computer skills Basic
Stability Stable
Maintained No


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Publication for PMes

PMes citations


Cold and Heat Stress Diversely Alter Both Cauliflower Respiration and Distinct Mitochondrial Proteins Including OXPHOS Components and Matrix Enzymes

Int J Mol Sci
PMCID: 5877738
PMID: 29547512
DOI: 10.3390/ijms19030877

[…]; []), NetPhos v2.0, available online: (; []) and MUsite v1.0 (Available online:; []). Methylation sites were predicted by PMes (Available online:; []). The data were compared with Arabidopsis data at PPDB (Available online: […]


Petri Net Based Model of Helicobacter pylori Mediated Disruption of Tight Junction Proteins in Stomach Lining during Gastric Carcinoma

Front Microbiol
PMCID: 5592237
PMID: 28932213
DOI: 10.3389/fmicb.2017.01682

[…] d within TJ proteins may be targeted for therapeutic interventions in diseased condition. In CLDN2, two arginine residues at location 112 and 210 are estimated to be potential methylation sites using PMes program (Figure ). These sites are highly conserved and located within intracellular cytoplasmic loop, thus can easily alter protein binding and loop conformations. Within CX32, five sites (R: 16 […]


Protein post translational modifications: In silico prediction tools and molecular modeling

Comput Struct Biotechnol J
PMCID: 5397102
PMID: 28458782
DOI: 10.1016/j.csbj.2017.03.004

[…] lso started to take into account other interesting properties, such as evolutionary information (e.g., PhosphoOrtholog, iUbiq), SASA (e.g., MASA, METhK, SUMOAMVR) and physiochemical properties (e.g., Pmes, SUMOhydro).Altogether, these approaches are only rarely considering the molecular features associated with PTMs and the molecular impact they have for protein function in general. Within this co […]


Mutation Structure Function Relationship Based Integrated Strategy Reveals the Potential Impact of Deleterious Missense Mutations in Autophagy Related Proteins on Hepatocellular Carcinoma (HCC): A Comprehensive Informatics Approach

Int J Mol Sci
PMCID: 5297772
PMID: 28085066
DOI: 10.3390/ijms18010139

[…] erver predicts probable sites on the basis of experimentally verified palmitoylation sites.Protein methylation plays a key role in PPIs which are the central players in almost every cellular process. PMes program, a support vector machine and enhanced feature based encoding scheme ( [] was used for the prediction of potential methylation sites. PMes se […]


Draft Genome Sequences of Sphingobium sp. Strain TCM1 and Sphingomonas sp. Strain TDK1, Haloalkyl Phosphate Flame Retardant and Plasticizer Degrading Bacteria

Genome Announc
PMCID: 4945803
PMID: 27417843
DOI: 10.1128/genomeA.00668-16

[…] phosphodiesterase (PDE), and phosphomonoesterase (PME). We identified PTEs capable of degrading TDCPP and TCEP in both strains and named them haloalkylphosphorus hydrolase (HAD) (). However, PDEs and PMEs involved in the degradation have not yet been identified.The genomic DNAs of TCM1 and TDK1 were sequenced by paired-end sequencing with an Illumina MiSeq platform (Illumina, San Diego, CA). The 1 […]


Evolution of disorder in Mediator complex and its functional relevance

Nucleic Acids Res
PMCID: 4770211
PMID: 26590257
DOI: 10.1093/nar/gkv1135
call_split See protocol

[…] reviseae, A. thaliana, O. saitva subsp. japonica, C. elegans, D. melanogaster, D. rerio, G. gallus and H. sapiens. PTMs were predicted with freely available web tools NetPhos 2.0 (), NetNGlyc 1.0 (), PMeS () and PAIL () with default parameters. A stretch of 30 residues in Mediator complex subunits was considered as PTM hotspot if the fraction of predicted PTM sites in this stretch was between 0.1 […]


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PMes institution(s)
Department of Chemistry, Nanchang University, Nanchang, China; Department of Mathematics, Nanchang University, Nanchang, China
PMes funding source(s)
Supported by grants from the National Natural Science Foundation of China (21175064, 21163014 and 21065006).

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