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POLYVIEW-MM specifications


Unique identifier OMICS_05074
Interface Web user interface
Restrictions to use None
Computer skills Basic
Stability Stable
Maintained Yes

Publication for POLYVIEW-MM

POLYVIEW-MM citations


Targeting substrate site in Jak2 kinase prevents emergence of genetic resistance

Sci Rep
PMCID: 4588578
PMID: 26419724
DOI: 10.1038/srep14538

[…] ed as ligands. The following parameters were used for docking simulations: ga_pop_size 150, ga_num_evals 50000000, and ga_run 200, with default spacing for grid boxes. The results were analyzed using Polyview-MM. […]


A Fungal P450 (CYP5136A3) Capable of Oxidizing Polycyclic Aromatic Hydrocarbons and Endocrine Disrupting Alkylphenols: Role of Trp129 and Leu324

PLoS One
PMCID: 3229547
PMID: 22164262
DOI: 10.1371/journal.pone.0028286

[…] specifically phenanthrene, pyrene, and 4-n-nonylphenol, were docked into the putative active site cavity. Contacting residues were identified from the top-scoring poses of the substrates () using the POLYVIEW-MM server . To pinpoint the residues critical for substrate recognition, multiple sequence alignment (MSA) was performed between the mammalian PAH oxidases (CYPs 1A2 and 3A4) and the novel PA […]


Survey of public domain software for docking simulations and virtual screening

Hum Genomics
PMCID: 3525969
PMID: 21807604
DOI: 10.1186/1479-7364-5-5-497

[…] is of multiple ligands docked to the receptor. The list of compounds and alternative poses can be sorted by the estimated binding energy, number of hydrogen bonds formed and other characteristics.The POLYVIEW-MM server [] combines multiple annotations for both the receptor structure and the protein-ligand interaction. Alternative poses of the ligand can be visualised and analysed using the Jmol ap […]

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POLYVIEW-MM institution(s)
Department of Environmental Health, University of Cincinnati, Cincinnati, OH, USA


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Anonymous user #961's avatar image No country

Anonymous user #961

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An online molecule viewer - and for what it does - it does it well - my only suggestion would be to provide a larger panel / frame in which to display the molecule in high resolution