Pool sequencing data analysis bioinformatics software tools

Whole-genome sequencing of pools of individuals (Pool-seq) provides a cost-effective alternative to sequencing individuals separately. With the availability of custom-tailored software tools, Pool-seq is being increasingly used for population genomic research on both model and…

Pool-seq analysis steps

Most recent bioinformatics tools

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Barcas
Desktop

Barcas

Permits analysis of multiplexed barcode-seq data. Barcas maps sequenced reads…

Permits analysis of multiplexed barcode-seq data. Barcas maps sequenced reads based on the trie data structure for fast and efficient imperfect matching. It constructs a trie data structure from the…

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RegressHaplo
Desktop

RegressHaplo

Reconstructs haplotypes using a penalized regression approach. RegressHaplo is…

Reconstructs haplotypes using a penalized regression approach. RegressHaplo is an algorithm developed to (i) split the genomic region of interest into subregions, (ii) construct local haplotypes for…

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Hexahedron
Web

Hexahedron

Aims users to reconstruct local and global sequences. Hexahedron can determine…

Aims users to reconstruct local and global sequences. Hexahedron can determine relative frequency of local and global sequences. It offers a visualization technique that represents the dynamic nature…

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AXE
Desktop

AXE

Allows demultiplexing 5’-indexed reads. Axe matches the prefix of a sequence…

Allows demultiplexing 5’-indexed reads. Axe matches the prefix of a sequence read against a pre-computed trie of index sequences. It starts by calculating all sequences within a given hamming…

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