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Pool sequencing data analysis bioinformatics software tools

Whole-genome sequencing of pools of individuals (Pool-seq) provides a cost-effective alternative to sequencing individuals separately. With the availability of custom-tailored software tools, Pool-seq is being increasingly used for population genomic research on both model and…

Pool-seq analysis steps

Most recent bioinformatics tools

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GRAMA
Desktop

GRAMA Genetic Recombinant Analysis and Mapping Assistant

Performs analyses of genetic mapping populations and generate mapping scores.…

Performs analyses of genetic mapping populations and generate mapping scores. GRAMA is a software tool that has been developed specifically for using temperature gradient capillary electrophoresis…

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OPENDoRM
Web

OPENDoRM Optimization of Pooled Experiments in NGS for Detection of Rare Mutations

Assists in planning next generation sequencing (NGS) experiments. OPENDoRM can…

Assists in planning next generation sequencing (NGS) experiments. OPENDoRM can be splits into four components: (i) global settings for the NGS experiment; (ii) data processing; (iii) visual…

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Barcas
Desktop

Barcas

Permits analysis of multiplexed barcode-seq data. Barcas maps sequenced reads…

Permits analysis of multiplexed barcode-seq data. Barcas maps sequenced reads based on the trie data structure for fast and efficient imperfect matching. It constructs a trie data structure from the…

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RegressHaplo
Desktop

RegressHaplo

Reconstructs haplotypes using a penalized regression approach. RegressHaplo is…

Reconstructs haplotypes using a penalized regression approach. RegressHaplo is an algorithm developed to (i) split the genomic region of interest into subregions, (ii) construct local haplotypes for…

Most popular analytical software and databases

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FreeBayes
Desktop

FreeBayes

A Bayesian genetic variant detector designed to find small polymorphisms,…

A Bayesian genetic variant detector designed to find small polymorphisms, specifically SNPs, indels, MNPs, and complex events smaller than the length of a short-read sequencing alignment.

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