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Population PK/PD modeling software tools | Drug discovery

Pharmacometrics is a scientific discipline that integrates pharmacokinetics, pharmacodynamics, pharmacology, physiology, knowledge about diseases, and statistics to quantify interactions between drugs and patients using mathematical models (Lee et…
PFIM
Desktop

PFIM

Evaluates and/or optimises population designs based on the expression of the…

Evaluates and/or optimises population designs based on the expression of the Fisher information matrix (FIM) in nonlinear mixed effects models. PFIM keeps improvements for models with inter-occasion…

Phxnlme
Desktop

Phxnlme

Facilitates the drug development process and provides improved graphical…

Facilitates the drug development process and provides improved graphical diagnostics. Phxnlme was designed to provide functionality for the major tasks that are usually performed in pharmacometric…

eDNAoccupancy
Desktop

eDNAoccupancy

Assists users in analyzing of data collected in eDNA-based surveys.…

Assists users in analyzing of data collected in eDNA-based surveys. eDNAoccupancy is an R package for fitting Bayesian, multi-scale occupancy models. This package allows users to (i) specify and fit…

WinBUGS
Desktop

WinBUGS

Aims to make practical Markov chain Monte Carlo (MCMC) methods available to…

Aims to make practical Markov chain Monte Carlo (MCMC) methods available to applied statisticians. WinBUGS allows models to be described using a slightly amended version of the BUGS language, or as…

JAGS
Desktop

JAGS Just Another Gibbs Sampler

Assists users in drawing samples from the joint posterior distribution of the…

Assists users in drawing samples from the joint posterior distribution of the parameters of a Bayesian model. JAGS is a free software package for analysis of Bayesian models. It uses a suite of…

NONMEM
Desktop

NONMEM NONlinear Mixed Effects Modeling

Fits models to many different types of data. NONMEM is based on classical…

Fits models to many different types of data. NONMEM is based on classical likelihood methods and Monte Carlo expectation-maximization and Markov Chain Monte Carlo (MCMC) Bayesian methods. It provides…

Phoenix NLME
Desktop

Phoenix NLME

Models population and realizes simulation for scientists with all levels of…

Models population and realizes simulation for scientists with all levels of experience—from the most advanced modelers to novice PK/PD scientists. Phoenix NLME includes integrated data preparation,…

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