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PosiGene specifications


Unique identifier OMICS_16821
Name PosiGene
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux
Programming languages Perl
License GNU General Public License version 3.0
Computer skills Advanced
Stability Stable
Maintained Yes




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  • person_outline Arne Sahm

Publication for PosiGene

PosiGene citations


Long lived rodents reveal signatures of positive selection in genes associated with lifespan

PLoS Genet
PMCID: 5884551
PMID: 29570707
DOI: 10.1371/journal.pgen.1007272

[…] archive) study prjeb20584., to scan on a genome-wide scale for genes under positive selection, we fed the cdss of the described species set along with the branches we wanted to examine () into the posigene pipeline []. giant mole-rat was used as posigene’s anchor species. orthology was determined by posigene via best bidirectional blast searches [, ] against the orthologs groups defined […]


The Kalanchoë genome provides insights into convergent evolution and building blocks of crassulacean acid metabolism

Nat Commun
PMCID: 5711932
PMID: 29196618
DOI: 10.1038/s41467-017-01491-7

[…] we also identified convergent changes in protein sequences of another two cazyme genes (kaladp0016s0058 [gt29] and kaladp0067s0114 [gh35]) that were under positive selection (codeml implemented in posigene, p < 0.05) in the dicot cam species k. fedtschenkoi and one of the two monocot cam species (a. comosus and p. equestris) (supplementary figs. –). kaladp0016s0058 encodes a putative […]

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PosiGene institution(s)
Leibniz Institute on Aging, Fritz Lipmann Institute, Jena, Germany
PosiGene funding source(s)
This work was supported by Leibniz-Gesellschaft through the Senatsausschusswettbewerb (SAW) [SAW-2012-FLI-2]; Deutsche Forschungsgemeinschaft (DFG) [PL 173/8-1].

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