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Positional effect correction software tools | DNA methylation microarray data analysis

Positional effect correction software tools | DNA methylation microarray data analysis Filtering out probes with potential errors and adjusting experimental bias have been necessary data pre-processing steps. There is also ‘positional effects’ that the same sample in different physical positions on the array could be measured as different methylation levels. The earliest mention of the positional effect in the Illumina gene expression microarray analysis did not provide a method for correction except an advisement to randomly set the samples in the array.
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