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Positional effect correction software tools | DNA methylation microarray data analysis

Filtering out probes with potential errors and adjusting experimental bias have been necessary data pre-processing steps. There is also ‘positional effects’ that the same sample in different physical positions on the array could be…
minfi
Desktop

minfi

A suite of computational tools that incorporate state-of-the-art statistical…

A suite of computational tools that incorporate state-of-the-art statistical techniques for the analysis of DNAm data. minfi provides methods for preprocessing, quality assessment and detection of…

posibatch
Desktop

posibatch

Removes the positional effects and batch effects in data preprocessing.…

Removes the positional effects and batch effects in data preprocessing. posibatch is based on the ComBat function. The tool uses either parametric or non-parametric empirical Bayes frameworks for…

ComBat
Desktop

ComBat

Adjusting batch effects in microarray expression data using Empirical Bayes…

Adjusting batch effects in microarray expression data using Empirical Bayes methods. The modified ComBat (M-Combat) is designed specifically in the context of meta-analysis and batch effect…

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