Postgwas statistics

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Postgwas specifications

Information


Unique identifier OMICS_04393
Name Postgwas
Software type Package/Module
Interface Command line interface
Restrictions to use None
Operating system Unix/Linux, Mac OS, Windows
Programming languages R
Computer skills Advanced
Version 1.11
Stability Stable
Maintained Yes

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Maintainer


  • person_outline Milan Hiersche <>

Publication for Postgwas

Postgwas in publications

 (3)
PMCID: 4631601
PMID: 26528553
DOI: 10.1371/journal.pone.0140301

[…] tissue (). note that reported p-values are not corrected for multiple testing., gsea was performed for any bacterial abundance gwas with at least one significantly associated snp using the r package postgwas[]. each tested snp was assigned to the closest gene using ensembl release 75 and any snp further than 10kb from a gene was eliminated from analysis. an aggregate gene-wise p-value […]

PMCID: 4706156
PMID: 26154020
DOI: 10.1016/j.neurobiolaging.2015.06.005

[…] cutoff level of p < 0.05 was used., to implement the pipeline analysis, we developed our own custom codes of the r v3.1.2 software (www.r-project.org/) by using the r packages snprelate, postgwas, spc, assotestr, multtest for read plink gwas files, compute ld, perform gates, spca, and skat analysis, and list adjusted p values, respectively., to assess the biological relevance […]

PMCID: 5019244
PMID: 26343929
DOI: 10.1002/sim.6605

[…] functions for sample‐level quality control and computationally efficient principal component (pc) calculation. other packages include functionalities for data visualization (ggplot2, ldheatmap, postgwas), data manipulation (plyr), and parallel processing (doparallel), as well as their dependencies. , we additionally specify the parameters used in the data processing and analysis. […]


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Postgwas institution(s)
Leibniz-Institute for Arteriosclerosis Research at the University Muenster, Muenster, Germany
Postgwas funding source(s)
Supported by grant 01GS0841 of the National Genome Research Network funded by the Bundesministerium fur Bildung und Forschung, Germany and by grants from the NRW/EU-Ziel2-Programm 2007–2013 ‘‘European Union, European Regional Development Fund, Investing in your Future’’ and the German federal state North Rhine-Westphalia.

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