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PPI spider specifications


Unique identifier OMICS_29105
Name PPI spider
Interface Web user interface
Restrictions to use None
Computer skills Basic
Maintained Yes


  • Primates
    • Homo sapiens


  • person_outline Alexey Antonov

Publication for PPI spider

PPI spider citations


Identification of Interactions in the NMD Complex Using Proximity Dependent Biotinylation (BioID)

PLoS One
PMCID: 4774922
PMID: 26934103
DOI: 10.1371/journal.pone.0150239

[…] ent of GO biological processes and the enrichment of InterPro annotations was calculated in Figs , , respectively. The analysis of the protein-protein interaction (PPI) network was performed with the PPI spider tool [] using the experimental binary interactions deposited in the IntAct database. The interaction network was visualized in Cytoscape 3.2.1 [] and graphically edited in Adobe Illustrator […]


Data for transcriptomic and iTRAQ proteomic analysis of Anguilla japonica gills in response to osmotic stress

PMCID: 4510098
PMID: 26217731
DOI: 10.1016/j.dib.2015.02.012

[…] GO and KEGG pathway analysis of the identified 965 proteins was conducted by DAVID . A protein–protein interaction (PPI) spider was used to construct an overview of the PPI information based on the global PPI network from the IntAct database . The Homo sapiens orthologs were based on homolog match using all of the […]


The Human Pancreatic Islet Transcriptome: Expression of Candidate Genes for Type 1 Diabetes and the Impact of Pro Inflammatory Cytokines

PLoS Genet
PMCID: 3297576
PMID: 22412385
DOI: 10.1371/journal.pgen.1002552

[…] InterPro and UCSC_TFBS for our DAVID analyses.Networks of pairwise interactions between proteins, as described in the IntAct database, were obtained from the lists of up/downregulated genes using the PPI_spider from the BioProfiling site (http://www.bioprofiling.de).We employed an approach similar to the one used to define cytokine-modified genes to compare the untreated control islets to the adi […]


MIPS: curated databases and comprehensive secondary data resources in 2010

Nucleic Acids Res
PMCID: 3013725
PMID: 21109531
DOI: 10.1093/nar/gkq1157

[…] n be divided into two categories. The first group [ProfCom (), PLIPS (), CCancer (), GeneSet2MiRNA ()] employs a modified enrichment analyses schema (). The second group [KEGG spider (), R spider (), PPI spider ()] implements a novel statistical methodology for the network-based interpretation of a gene list. Finally, GeneSet2MiRNA provides statistical information whether or not a query gene list […]


Characterizing Tyrosine Phosphorylation Signaling in Lung Cancer Using SH2 Profiling

PLoS One
PMCID: 2957407
PMID: 20976048
DOI: 10.1371/journal.pone.0013470

[…] SH2 domain binding data were input into PPI Spider (http://mips.helmholtz-muenchen.de/proj/ppispider/). Analyses were run with 100 random networks and only proteins that directly connect to each other through no more than one edge were allo […]


The early asthmatic response is associated with glycolysis, calcium binding and mitochondria activity as revealed by proteomic analysis in rats

PMCID: 2925830
PMID: 20691077
DOI: 10.1186/1465-9921-11-107

[…] c analysis on the identified proteins, including the gene ontology (GO) classification, the protein-protein interaction (PPI) networking and the biological pathway exploration, were carried out using PPI Spider [] and KEGG (Kyoto Encyclopedia of Genes and Genomes) Spider [], which are two freely available web-based tools for the interpretation of experimentally derived protein lists in the context […]


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PPI spider institution(s)
GSF National Research Center for Environment and Health, Institute for Bioinformatics, Neuherberg, Germany; Department of Genome-Oriented Bioinformatics, Wissenschaftszentrum Weihenstephan, Technische Universitat Munchen, Freising, Germany

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